Results 261 to 270 of about 217,152 (350)

EFFECTIVENESS OF EARLY USE OF SPONTANEOUS RESPIRATION UNDER CONTINUOUS POSITIVE AIRWAY PRESSURE IN PREMATURE INFANTS WITH VERY LOW BODY WEIGHT AT BIRTH

, 2017
Satsita S. Khasanova, A. L. Batmanov
openalex   +2 more sources

Mechanical Stress Induced NOX2 Promotes Endothelial Dysfunction in Ventilator‐Induced Lung Injury: Potential Treatment with Quercetin

Advanced Science, Volume 12, Issue 28, July 24, 2025.
Abnormal mechanical stretch induced by mechanical ventilation (MV) disrupts endothelial junctions via the NOX2/ROS/CaMKII/ERK1/2 axis both in human aortic endothelial cells (HAECs) in vitro and in ventilator‐induced lung injury (VILI) in mice. Quercetin, an antioxidant predicted to bind to NOX2, can effectively prevent mechanical stretch‐induced ...
Tao Jiang, Yabing Zhang, Zhiye Guo, He Ren, Weiyi Hu, Qingping Yao, Yunlong Huo, Yingxin Qi, Kai Huang   +8 more
wiley   +1 more source

Physiological Confounds in BOLD-fMRI and Their Correction. [PDF]

NMR Biomed
Addeh A, Williams RJ, Golestani A, Pike GB, MacDonald ME.   +4 more
europepmc   +1 more source

Mesencephalic Astrocyte‐Derived Neurotrophic Factor Binds BAX to Preserve Mitochondrial Homeostasis and Energy Metabolism for Relieving Myocardial Hypertrophy

Advanced Science, EarlyView.
MANF in cardiomyocytes interacts with BAX to impede BAX mitochondrial translocation and cytochrome c release, further stabilizing mitochondrial structure and energy supply to relieve myocardial apoptosis and hypertrophy, which indicates MANF as a novel cardioprotective factor to have a promising clinical application for myocardial hypertrophy ...
Dong Wang, Xinru Zhang, Baolong Wang, Haipeng Li, Dongshuo Xu, Yun Yang, Jialu Zhang, Wenbing Wang, Ren Zhang, Xinyu Wang, Yunfeng Cai, Shiyu Cao, Chao Hou, Changhui Wang   +13 more
wiley   +1 more source

A Synergistic Approach Using Photoacoustic Spectroscopy and AI-Based Image Analysis for Post-Harvest Quality Assessment of Conference Pears. [PDF]

Molecules
Petrus M, Popa C, Bratu AM, Bercu V, Gebac L, Mihai DM, Butcaru AC, Stanica F, Gogot R.   +8 more
europepmc   +1 more source

Nano‐Anesthetics Regulate Neuro‐Immune Interaction for Treating Neuropathic Pain

Advanced Science, EarlyView.
Ce‐UiO‐66‐Bupivacaine (CUB) demonstrates triple therapeutic innovation: 1) Sustained analgesia with ROS scavenging synergistically resolves neuropathic pain; 2) Microglia/astrocyte polarization switch reprograms the pro‐regenerative immune microenvironment; 3) CGRP‐TSP‐1 axis activation couples inflammation suppression to axon regeneration, defining a ...
Yue Wang, Xiuru Ji, Yu Sun, Han Wang, Ting Wang, Tao Luo, Yanyong Cheng, Jia Yan, Dalong Ni, Hong Jiang   +9 more
wiley   +1 more source

Central Sleep Apnea in Adults: An Interdisciplinary Approach to Diagnosis and Management-A Narrative Review. [PDF]

J Clin Med
Csipor Fodor A, Huțanu D, Budin CE, Ianoși MB, Rachiș DL, Sárközi HK, Vultur MA, Jimborean G.   +7 more
europepmc   +1 more source

NAT10 Increases Lysosomal Acidification to Promote Esophageal Cancer Metastasis via ac4C Acetylation of ATP6V0E1 mRNA

Advanced Science, EarlyView.
Zhan et al. demonstrate the vital role of NAT10‐catalyzed ac4C modification in regulating autophagy‐associated lysosomal acidification. They uncover the clinical and biological significance of ATP6V0E1, an important v‐ATPase assembly subunit, in tumor metastasis, particularly in the malignant progression of ESCC.
Yu‐Juan Zhan, Chun‐Miao Deng, Lin Tang, Shu‐Jun Li, Tao‐Yang Xu, Xian Wei, Xin‐Yi Zhang, Can‐Can Zheng, Li Deng, Cui Shao, Zhong‐Min Ouyang, Alfred King‐Yin Lam, Rong Zhang, Jun Liu, Xing‐Yuan Shi, Zhen‐Yu Pan, Wei Dai, Ming‐Liang He, Simon Law, Xu Li, Xiao‐Bing Chen, Cheng Zhou, Bin Li, Wen‐Wen Xu   +23 more
wiley   +1 more source

Effects of SGLT2 Inhibitors on Sleep Apnea Parameters and Cheyne-Stokes Respiration in Patients with Acute Decompensated Heart Failure: A Prospective Cohort Study. [PDF]

Biomedicines
Kalaydzhiev P, Velikova T, Davidkova Y, Voynova G, Borizanova A, Spasova N, Georgieva N, Ilieva R, Kinova E, Goudev A.   +9 more
europepmc   +1 more source

HLA‐DR⁺ Tumor Cells Show an Association with a Distinct Immune Microenvironment and CD8⁺ T‐Cell Exhaustion in HBV‐Associated Hepatocellular Carcinoma

Advanced Science, EarlyView.
This study integrates scRNA‐seq, multiplex immunofluorescence, and clinical data to identify HLA‐DR⁺tumor cells uniquely enriched in Hepatocellular carcinoma (HCC) with hepatitis B virus (HBV). These cells express MHC II, associate with PD‐L1, recruit and exhaust CD8⁺T cells, predict poor survival, and serve as potential biomarkers for immunotherapy ...
Jun‐Qing Chang, Yan Guo, Wen‐Jing Yuan, Yu‐Man Chen, Bo‐Wei Liu, Wen‐Tao Li, Xiang‐Ming Ding, Xu‐Dong Fu, Yu‐Han Lou, Zhuo‐Ran Chen, Xiao‐Ying Luo, Song‐Ze Ding, Bing‐Yong Zhang, Xiu‐Ling Li, Yong‐Zhi Hong, Shun‐Dong Cang, Dong‐Xiao Li, Ling Lan   +17 more
wiley   +1 more source