Results 241 to 250 of about 104,748 (300)

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

Holistic integrative analysis of circulatory parameters: effects of CPAP titration in patients with obstructive sleep apnea. [PDF]

J Thorac Dis
Chen JH, Sun XG, Xiang MJ, Zhang ZF, Huang J, Xie B, Xu F, Zhou QQ, Wang JN, Zhang YF, Shi C, Liu F, Xie YH.   +12 more
europepmc   +1 more source

From Defense Executor to Engineering Target: Harnessing Lignin for Crop Resistance

Advanced Science, EarlyView.
Lignin serves as both a physical and chemical executor of broad‐spectrum plant immunity. This review systematically summarizes classical and recent advances in lignin‐mediated immunity, outlines the multifaceted regulatory modules controlling lignification under biotic stress, discusses key physiological and biochemical mechanisms behind lignin‐based ...
Yanwen Yu, Ke Wang, Huachuan Tuo, Jiankun Li, Liping Xu, Chang‐Jun Liu, Mingyue Gou   +6 more
wiley   +1 more source

Right Ventricular Pressure-Volume Loop Analysis in Large Animal Research: A Scoping Review of Current Practices Using Conductance and Admittance Catheters. [PDF]

Pulm Circ
Orlitová M, Hellinck J, Dam Lyhne M, Granfeldt A, Neyrinck AP, Verbelen T, Claus P.   +6 more
europepmc   +1 more source

Designer Dynamic DNA Nanoaggregate in Living Cell for Mitochondrial Energy Restriction

Advanced Science, EarlyView.
This study presents the Tech‐tetrahedron, a designer dynamic DNA nanoaggregate engineered for precise mitochondrial energy restriction. Its trinity‐functionalized design integrates navigable unit, telomerase‐activated latch, and self‐assembly module.
Ruijia Deng, Jing Sheng, Ben Niu, Wenjuan Fu, Yingjie Yang, Zuowei Xie, Shuang Xie, Yunxuan He, Meilin Gong, Jue Wang, Yan Pi, Ming Chen, Kai Chang   +12 more
wiley   +1 more source

ADP-dependent platelet activation is required for thrombus formation in mice exposed to simulated flight conditions. [PDF]

Blood Vessel Thromb Hemost
Tourn J, Carminita E, Crescence L, Adjriou N, Guieu R, Dubois C, Panicot-Dubois L.   +6 more
europepmc   +1 more source

Evaluating the Air Respiratory Capacity of Awaous (Chonophorus) tajasica (Gobiiformes: Oxudercidae): A Morpho-Functional Study. [PDF]

J Exp Zool A Ecol Integr Physiol
Trevisan JP, Venturelli D, Klein W, Cruz ALD.   +3 more
europepmc   +1 more source

GPT2-mediated Glutamate to α-Ketoglutaric Acid Conversion in Cardiac Fibroblast Promotes Fibrosis. [PDF]

JACC Basic Transl Sci
Chen Y, Liao F, Wang J, Zhao J, Xu Y, Chen Q, Hong T, Lv K, Li Q, Chen X, Xiao C, Wang L, Li G, Ke C, Cai J, Li J, Sheng S, Wang J, Wu X, Ruan Y, Zhang F, Wu R, Xu Y, Zhu W, Xu Y, Wang J, Ni C, Hu X.   +27 more
europepmc   +1 more source

Gut Microbiomes of Marine Zooplankton: Consequences for Host Performance, the Biological Carbon Pump, and Prokaryote Biogeography. [PDF]

Environ Microbiol
Calbet A.
europepmc   +1 more source

The Separate Roles of Vascular Plants and Sphagnum Mosses in Regulating the Net CO₂ Exchange in a Boreal Peatland During Key Phenological Phases. [PDF]

Glob Chang Biol
Hartmann A, Hikino K, Guth L, Simpson G, Järveoja J, Nilsson MB, Peichl M.   +6 more
europepmc   +1 more source