Results 231 to 240 of about 7,373,496 (288)

Metabolic Memory in Cardiovascular Disease: Encoding, Propagation, and Therapeutic Targeting

open access: yesAdvanced Science, EarlyView.
Cardiovascular risk often persists after metabolic abnormalities are corrected. This conceptual Review frames such persistence as metabolic memory, encoded through a narrowing therapeutic window from reversible marks to irreversible damage, with continuous input from peripheral organs.
Cheng Cheng   +12 more
wiley   +1 more source

5D Flow MRI Reveals Respiration-Driven Changes in Blood Flow Energetics in Congenital Heart Disease. [PDF]

open access: yesMagn Reson Med
Nallamothu T   +7 more
europepmc   +1 more source

Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants

open access: yesAdvanced Science, EarlyView.
Conformational plasticity governs SARS‐CoV‐2 spike function and ACE2 recognition. Using high‐speed AFM and single‐molecule force spectroscopy, we analyzed the ancestral spike and nine variants, revealing progressive rigidification from Delta, variable plasticity in Omicron sublineages, and JN.1 compaction.
Sarah Stainer   +17 more
wiley   +1 more source

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