Results 51 to 60 of about 315,034 (346)

Early Prone versus Supine Positioning in Moderate to Severe Coronavirus Disease 2019 Patients with Acute Respiratory Distress Syndrome

Oman Medical Journal, 2023
Objectives: This study sought to determine whether early prone positioning of patients with moderate to severe COVID-19-related acute respiratory distress syndrome (ARDS) lowers the mortality rate.
Abdul Hakeem Al Hashim, Ibrahim Al Zakwani, Abdullah Al Jadidi, Ruqaiya Al Harthi, Maadh Al Naabi, Ramakrishna Biyappu, Sonali Kodange, Naveen Kumar Asati, Tamadher Al Barhi, Mudhun Mohan, Jayachandiran Jagadeesan, Micheline Sachez, Praisemabel S. Sycaayao, Khalfan Al Amrani, Huda Al Khalili, Rashid Al Mamari, Mujahid Al-Busaidi   +16 more
doaj   +1 more source

Multitask Network for Respiration Rate Estimation -- A Practical Perspective [PDF]

arXiv, 2021
The exponential rise in wearable sensors has garnered significant interest in assessing the physiological parameters during day-to-day activities. Respiration rate is one of the vital parameters used in the performance assessment of lifestyle activities. However, obtrusive setup for measurement, motion artifacts, and other noises complicate the process.
arxiv  

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

Molecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang, Haimei Wen, Ying Chen, Jingya Ning, Di Hu, Yujiao Dong, Chenyu Yao, Bo Yuan, Shuanying Yang   +8 more
wiley   +1 more source

Pressure- vs. volume-controlled ventilation and their respective impact on dynamic parameters of fluid responsiveness: a cross-over animal study

BMC Anesthesiology, 2023
Background and goal of study Pulse pressure variation (PPV) and stroke volume variation (SVV), which are based on the forces caused by controlled mechanical ventilation, are commonly used to predict fluid responsiveness.
Amelie Zitzmann, Tim Bandorf, Jonas Merz, Fabian Müller-Graf, Maria Prütz, Paul Frenkel, Susanne Reuter, Brigitte Vollmar, Nora A. Fuentes, Stephan H. Böhm, Daniel A. Reuter   +10 more
doaj   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

A method for improving recognition of lying postures using a measured signal intensity of respiration and heartbeat

Nihon Kikai Gakkai ronbunshu, 2018
We describe a method for improving recognition of lying postures using a measured signal intensity of respiration and heartbeat. We have proposed a measurement method of lying posture, respiration, and heartbeat using a Smart Rubber sensor, a rubber ...
Kazuya MATSUO, Toshiharu MUKAI, Shijie GUO   +2 more
doaj   +1 more source

2-D Respiration Navigation Framework for 3-D Continuous Cardiac Magnetic Resonance Imaging [PDF]

arXiv, 2020
Continuous protocols for cardiac magnetic resonance imaging enable sampling of the cardiac anatomy simultaneously resolved into cardiac phases. To avoid respiration artifacts, associated motion during the scan has to be compensated for during reconstruction.
arxiv  

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Capnothorax During Laparoscopy in Trendelenburg Position: A Rare Case Study

Acta Médica Portuguesa, 2020
Pneumothorax is an infrequent complication of laparoscopic surgery. Most cases occur during upper abdominal surgery, since a head-down position (Trendelenburg) pushes the liver and peritoneum against the diaphragm, reducing gas release.
Ana Margarida Damas, Fátima Gonçalves, Marisa Antunes, Sónia Barata   +3 more
doaj   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

FEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen   +14 more
wiley   +1 more source