Results 41 to 50 of about 13,326,383 (314)

Predictive modelling of Australian school principals’ turnover intentions using machine learning with random effects

Discover Computing
This study identifies key predictors of Australian school principals’ turnover intention, using a machine learning approach—extreme gradient boosting (XGBoost) with random effects.
Jiesi Guo, Danling Huang, Jinran Wu, Hamed Mogouie, Theresa Dicke   +4 more
doaj   +1 more source

Targeting HER2-positive breast cancer: advances and future directions

Nature reviews. Drug discovery, 2022
The discovery of the monoclonal antibody trastuzumab almost 25 years ago revolutionized treatment and drug development for HER2^+ breast cancer. Here, Swain et al.
S. Swain, M. Shastry, E. Hamilton
semanticscholar   +1 more source

Rational Use of Herbal Products in Pediatric Patients Treated With Anticancer Drugs in the European Union

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot, Mathieu Corvaisier, Laurence Spiesser‐Robelet, Mylène Duplan, Isabelle Pellier, Delphine Bourneau‐Martin, Séverine Derbré   +6 more
wiley   +1 more source

Accurate Fault Location Algorithm for Untransposed Transmission Lines Based on Network Phasor Equations in Positive-, Negative-, and Zero-Sequences Domain During Fault

IEEE Access
The tower structure and geometrical arrangement of transmission line conductors in the power system depend on various technical, economic, and geographical factors and the age of construction of the lines.
Mahyar Abasi
doaj   +1 more source

Trastuzumab Emtansine for HER2-Positive Advanced Breast Cancer

New England Journal of Medicine, 2012
Background Trastuzumab emtansine (T-DM1) is an antibody–drug conjugate incorporating the human epidermal growth factor receptor 2 (HER2)–targeted antitumor properties of trastuzumab with the cytotoxic activity of the microtubule-inhibitory agent DM1. The
S. Verma, D. Miles, L. Gianni, I. Krop, M. Welslau, J. Baselga, M. Pegram, D. Oh, V. Diéras, Ellie Guardino, L. Fang, Michael W. Lu, S. Olsen, K. Blackwell   +13 more
semanticscholar   +1 more source

Improved Early Referral in Long‐Term Survivor Care With Institutional Standardized Practice Among Childhood Leukemia Survivors#

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In 2018, the Texas Children's Cancer and Hematology Center Leukemia Program implemented a practice standard to support the transition from treatment to survivorship that includes shared, alternating care between leukemia and survivorship clinicians and a reminder to refer survivors to the long‐term survivor clinic (LTSC) 2 years after ...
Ji Yun Tark, Kayla L. Foster, Omar Shakeel, Mary C. Shapiro, Shawki L. Qasim, ZoAnn Dreyer, Eric S. Schafer, Ashley M. Butler, Austin L. Brown, Maria Monica Gramatges   +9 more
wiley   +1 more source

Understanding gender and age differences in language use: cross-cultural insights from Weibo and Facebook

Humanities & Social Sciences Communications
This study integrates social role theory and socioemotional selectivity theory to investigate the cultural universalities and differences in language use among male and female users across different age groups on Weibo and Facebook.
Dandan Pang, Sharath Chandra Guntuku, Garrick Sherman, Tingting Liu, Sunny Rai, Young-Min Cho, Rian You, Arnold B. Bakker, Lyle H. Ungar   +8 more
doaj   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source

Relationship between quality of life and the metabolic- nutritional profile of individuals with type 2 diabetes mellitus

O Mundo da Saúde, 2017
Knowing the quality of life and life satisfaction among the diabetic population can help in the development of food and nutritional education strategies, public policies related to food and nutritional security, as well as result additional benefits to
Débora Luciana de Oliveira, Mayara Stawicki, Thais Regina Mezzomo   +2 more
doaj  

Efficacy of Larotrectinib in TRK Fusion–Positive Cancers in Adults and Children

New England Journal of Medicine, 2018
Background Fusions involving one of three tropomyosin receptor kinases (TRK) occur in diverse cancers in children and adults. We evaluated the efficacy and safety of larotrectinib, a highly selective TRK inhibitor, in adults and children who had tumors ...
A. Drilon, T. Laetsch, S. Kummar, S. DuBois, U. Lassen, G. Demetri, M. Nathenson, R. Doebele, A. Farago, A. Pappo, B. Turpin, A. Dowlati, M. Brose, L. Mascarenhas, N. Federman, J. Berlin, W. El-Deiry, C. Baik, J. Deeken, V. Boni, R. Nagasubramanian, Matthew H. Taylor, E. Rudzinski, F. Meric-Bernstam, D. Sohal, P. Ma, L. Raez, J. Hechtman, R. Benayed, M. Ladanyi, Brian B. Tuch, K. Ebata, S. Cruickshank, N. Ku, M. Cox, D. Hawkins, D. Hong, D. Hyman   +37 more
semanticscholar   +1 more source