Results 31 to 40 of about 13,326,383 (314)

Client characteristics and outcomes of the Australian short-term restorative care programme: a cohort study

BMC Health Services Research
Background Restorative care is a goal-oriented, time-limited, multidisciplinary approach to address functional decline in older adults. Within Australia, one form of restorative care available to community-dwelling older adults is the Short-Term ...
Lindsey Brett, Angela Collins, Kylie Lemsing, Christopher J. Poulos   +3 more
doaj   +1 more source

Risk factors of intimate partner violence in women attending a community-based sexual health center: Perceived discrimination as a key factor

Ψυχολογία: το Περιοδικό της Ελληνικής Ψυχολογικής Εταιρείας
Gender-based violence (GBV), specifically intimate partner violence (IPV), is a global problem that predominantly impacts women. This study aimed to investigate IPV among women visiting community sexually transmitted infections’ prevention and testing ...
Άννα Αποστολίδου, Σταυρούλα Τριανταφυλλίδου, Κλάρα Βλαχοδημητροπούλου Rodriguez, Παρασκευή Σιαμήτρου, Κωνσταντίνος Πρωτόπαπας, Γεώργιος Παπαδοπετράκης, Ανδρέας Πασπαλάκης, Ευαγγελία Ντινοπούλου, Στέργιος Μάτης, Αμαλία Μανωλοπούλου, Γεωργία Κούτση, Νίκος Βέγκος, Ανδρέας Ασλάνης, Αναστασία Αντωνιάδου, Λίσσυ Κανελλοπούλου, Αντώνης Πούλιος   +15 more
doaj   +1 more source

Trastuzumab Deruxtecan in Previously Treated HER2-Positive Breast Cancer

New England Journal of Medicine, 2019
BACKGROUND Trastuzumab deruxtecan (DS-8201) is an antibody-drug conjugate composed of an anti-HER2 (human epidermal growth factor receptor 2) antibody, a cleavable tetrapeptide-based linker, and a cytotoxic topoisomerase I inhibitor.
S. Modi, C. Saura, T. Yamashita, Yeon-Hee Park, Sung-Bae Kim, K. Tamura, F. André, H. Iwata, Yoshinori Ito, J. Tsurutani, J. Sohn, N. Denduluri, C. Perrin, K. Aogi, E. Tokunaga, S. Im, K. Lee, S. Hurvitz, J. Cortés, Caleb Lee, Shuquan Chen, Lin Zhang, J. Shahidi, A. Yver, I. Krop   +24 more
semanticscholar   +1 more source

Cup‐Like Nuclei Is a Hallmark of DUX4/ERG Acute Lymphoblastic Leukemia and Reveals Cytoplasmic Mitochondria Accumulation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille, Hugo Roux, Odile Fenneteau, Aurélie Caye‐Eude, Alexia Kinoo, Yoann Vial, André Baruchel, Marion Strullu, Elodie Lainey, Hélène Cavé   +9 more
wiley   +1 more source

Trastuzumab Emtansine for Residual Invasive HER2‐Positive Breast Cancer

New England Journal of Medicine, 2019
Background Patients who have residual invasive breast cancer after receiving neoadjuvant chemotherapy plus human epidermal growth factor receptor 2 (HER2)–targeted therapy have a worse prognosis than those who have no residual cancer.
G. von Minckwitz, Chiun-Sheng Huang, M. Mano, S. Loibl, E. Mamounas, M. Untch, N. Wolmark, P. Rastogi, A. Schneeweiss, A. Redondo, H. Fischer, W. Jacot, A. Conlin, C. Arce-Salinas, I. Wapnir, C. Jackisch, M. DiGiovanna, P. Fasching, J. Crown, P. Wülfing, Z. Shao, E. R. Caremoli, Haiyan Wu, L. Lam, D. Tesarowski, M. Smitt, Hannah Douthwaite, S. Singel, C. Geyer   +28 more
semanticscholar   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger, Efrat Bar‐Ilan, Victoria Marcu, Evgeny Grishin, Rinat Yacobi, Aviv Barzilai, Hana Golan, Assaf Arie Barg   +7 more
wiley   +1 more source

The Combined Effect of Obesity and Contraceptive Use on Pulmonary Embolism in Adolescent Females Residing in the United States

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Combined oral contraceptive (COC) use in obese adult women dramatically increases the relative risk of developing a pulmonary embolism (PE). The risk of a PE in obese adolescent females taking contraceptives is currently unknown. The purpose of this investigation was to determine the effect of body mass index (BMI) and contraceptive
John Puetz, Joanne Salas
wiley   +1 more source

Learn to be happy—an experimental study in clinical context with depressive patients in Germany

Frontiers in Psychology
The increase in the number of people with mental disorders and the relapse rate of depressive patients give reason to constantly question and further develop psychotherapeutic interventions in order to stabilize therapy effects. Studies show that the art
Elena Renée Sequeira-Nazaré, Bernhard Schmitz   +1 more
doaj   +1 more source

Positive Psychology: Looking Back and Looking Forward

Frontiers in Psychology, 2022
Envisioning the future of positive psychology (PP) requires looking at its past. To that end, I first review prior critiques of PP to underscore that certain early problems have persisted over time.
Carol D. Ryff
doaj   +1 more source

Positive-unlabeled convolutional neural networks for particle picking in cryo-electron micrographs [PDF]

Nature Methods, 2018
Cryo-electron microscopy is a popular method for the determination of protein structures; however, identifying a sufficient number of particles for analysis can take months of manual effort.
T. Bepler, Andrew Morin, M. Rapp, J. Brasch, L. Shapiro, A. Noble, B. Berger   +6 more
semanticscholar   +1 more source