Results 11 to 20 of about 13,326,383 (314)

Capivasertib in Hormone Receptor–Positive Advanced Breast Cancer

open access: yesNew England Journal of Medicine, 2023
BACKGROUND AKT pathway activation is implicated in endocrine-therapy resistance. Data on the efficacy and safety of the AKT inhibitor capivasertib, as an addition to fulvestrant therapy, in patients with hormone receptor–positive advanced breast cancer ...
N. Turner   +22 more
semanticscholar   +1 more source

Cluster failure: Why fMRI inferences for spatial extent have inflated false-positive rates [PDF]

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2015
Significance Functional MRI (fMRI) is 25 years old, yet surprisingly its most common statistical methods have not been validated using real data. Here, we used resting-state fMRI data from 499 healthy controls to conduct 3 million task group analyses ...
A. Eklund   +2 more
semanticscholar   +1 more source

Measurement of the Positive Muon Anomalous Magnetic Moment to 0.46 ppm. [PDF]

open access: yesPhysical Review Letters, 2021
We present the first results of the Fermilab National Accelerator Laboratory (FNAL) Muon g-2 Experiment for the positive muon magnetic anomaly a_{μ}≡(g_{μ}-2)/2.
B. Abi   +236 more
semanticscholar   +1 more source

Use of CAR-Transduced Natural Killer Cells in CD19-Positive Lymphoid Tumors

open access: yesNew England Journal of Medicine, 2020
BACKGROUND Anti-CD19 chimeric antigen receptor (CAR) T-cell therapy has shown remarkable clinical efficacy in B-cell cancers. However, CAR T cells can induce substantial toxic effects, and the manufacture of the cells is complex.
E. Liu   +26 more
semanticscholar   +1 more source

An Australian aged care home for people subject to homelessness: health, wellbeing and cost–benefit

open access: yesBMC Geriatrics, 2023
Background Older people subject to homelessness face many challenges including poor health status, geriatric syndromes, and depression, coupled with barriers in accessing health and aged care services.
Claire M. C. O’Connor   +13 more
doaj   +1 more source

A Systematic Review of Machine Learning for Assessment and Feedback of Treatment Fidelity

open access: yesPsychosocial Intervention, 2021
Many psychological treatments have been shown to be cost-effective and efficacious, as long as they are implemented faithfully. Assessing fidelity and providing feedback is expensive and time-consuming.
Asghar Ahmadi   +11 more
doaj   +1 more source

The positive aspects in the writings of some orientalists on the Prophet Muhammad [PDF]

open access: yesمجلة جامعة الأنبار للعلوم الإنسانية, 2021
The study of the positive aspects in the writings of some orientalists on the Prophet Muhammad was of great importance in our research in to find out their opinions and sayings in the Messenger, and in the principles that Islam brought forth, and what ...
Zaynab Mahdy Raaowf
doaj   +1 more source

CDK inhibitors: positive and negative regulators of G1-phase progression.

open access: yesGenes & Development, 1999
Mitogen-dependent progression through the first gap phase (G1) and initiation of DNA synthesis (S phase) during the mammalian cell division cycle are cooperatively regulated by several classes of cyclin-dependent kinases (CDKs) whose activities are in ...
C. Sherr, J. M. Roberts
semanticscholar   +1 more source

Reliability of GENEActiv accelerometers to estimate sleep, physical activity, and sedentary time in children

open access: yesInternational Journal of Behavioral Nutrition and Physical Activity, 2021
Background Reliable estimates of habitual sleep, physical activity, and sedentary time are essential to investigate the associations between these behaviours and health outcomes.
Devan Antczak   +4 more
doaj   +1 more source

Positive Announcements [PDF]

open access: yesStudia Logica, 2020
Arbitrary public announcement logic (APAL) reasons about how the knowledge of a set of agents changes after true public announcements and after arbitrary announcements of true epistemic formulas. We consider a variant of arbitrary public announcement logic called positive arbitrary public announcement logic (APAL+), which restricts arbitrary public ...
Hans van Ditmarsch   +2 more
openaire   +2 more sources

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