Results 111 to 120 of about 306,713 (303)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Gröbner bases and Diophantine analysis
, 2008 A novel application of Gröbner bases to study the number of positive solutions to systems of generalised Pell equations is proposed and ...
Cipu, Mihai
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Numerical calculation of h-bases for positive dimensional varieties
, 2011 A symbolic-numeric method for calculating an H-basis for the ideal of a positive dimensional complex affine algebraic variety, possibly defined numerically, is given. H-bases for ideals I in C[x] = C[x1, . . .
Barry H Dayton
core
Distributions of coverage depths at all bases and at error bases.
, 2013 Distributions of coverage depths at error bases (red curves) are compared with those at all bases (blue curves) in the Velvet assemblies of three bacterial genomes: E. coli (A), S. aureus (B), and M.
Tzen-Yuh Chiang (138945) +4 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
, 2003 A subset A⊆N0 is called a basis of order h if every positive integer can be represented as a sum of h members of A. Thin bases of order h will be constructed in this paper, for each h⩾2, where the value of limsupA(n)/nh is smaller than that of thin bases
Blomer, Valentin
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Bases for cluster algebras from orbifolds
, 2017 We generalize the construction of the bracelet and bangle bases defined in [36] and the band basis defined in [43] to cluster algebras arising from orbifolds.
Pavel Tumarkin +3 more
core +1 more source