Results 131 to 140 of about 5,889,360 (355)

A Porcine Monoclonal Antibody Targeting a Conserved GP4 Epitope Protects against In Vivo Infection via the Induction of Broad‐Spectrum PRRSV Neutralization

Advanced Science, EarlyView.
This study developed mAb‐5F2, a monoclonal antibody targeting conserved GP4 residues (Q48/I50), which blocks the GP4‐CD163 interaction, resulting in a 78–85% reduction in viral entry. Porcineized 5F2‐pFc prevented mortality in infected piglets, reduced pulmonary viral loads, and minimized lesions. This broad‐spectrum antibody platform overcomes vaccine
Xu Chen, Jiakai Zhao, Pinpin Ji, Xiaoxuan Li, Hui Niu, Dian Jiao, Lu Zhang, Qianyi Zhu, Xinyu Liu, Julian A. Hiscox, James P. Stewart, Yani Sun, Qin Zhao   +12 more
wiley   +1 more source

Homogenization of a Continuously Microperiodic Multidimensional Medium

Trends in Computational and Applied Mathematics, 2018
The asymptotic homogenization method is applied to obtain formal asymptotic solution and the homogenized solution of a Dirichlet boundary-value problem for an elliptic equation with rapidly os- cillating coefficients.
Marcos Pinheiro Lima, Leslie Darien Pérez Fernández, Julián Bravo Castillero   +2 more
doaj   +1 more source

On positive-definite integral kernels and a related quadratic form. [PDF]

, 1958
Joshua Chover, Jacob J. Feldman
openalex   +1 more source

Globotriaosylceramide Gb3 Influences Wound Healing and Scar Formation by Orchestrating Fibroblast Heterogeneity

Advanced Science, EarlyView.
In superficial second‐degree burn wounds, Gb3 turns on genes related to papillary cells through the FGF2 signaling pathway. This increases the ability of cells to break down fibrin and decreases fibrosis, which ultimately prevents scar formation in burn injuries.
Sujie Xie, Runzhi Huang, Weijin Qian, Xinran Ding, Wei Zhang, Yixu Li, Jianyu Lu, Hanlin Sun, Yifan Liu, Yuntao Yao, Bingnan Lu, Minjuan Wu, Zhaofan Xia, Shizhao Ji   +13 more
wiley   +1 more source

Integral Representations of Positive Definite Functions. II [PDF]

, 1954
A. Devinatz
openalex   +1 more source

Treating Hearing Loss: From Cochlear Implantation to Gene Therapy

Advanced Science, EarlyView.
Cochlear implantation is the primary treatment for deafness, restoring functional hearing in over a million people. Recently, gene therapy has enabled biological hearing restoration in a small number of patients with OTOF‐related mutations. This perspective evaluates both approaches, concluding that cochlear implants will remain the standard for most ...
Fan‐Gang Zeng, Jieyu Qi, Chen‐Chi Wu, Yilai Shu, Renjie Chai   +4 more
wiley   +1 more source

A comparison of several methods for inverting large symmetric positive definite matrices [PDF]

, 1964
M. H. Lietzke, R. W. Stoughton, M.P. Lietzke   +2 more
openalex   +2 more sources

Tapping into Permutation Symmetry for Improved Detection of k-Symmetric Extensions. [PDF]

Entropy (Basel), 2023
Li Y, Zhang C, Hou SY, Wu Z, Zhu X, Zeng B.   +5 more
europepmc   +1 more source

Solving systems of linear equations with a positive definite, symmetric, but possibly ill-conditioned matrix [PDF]

, 1955
James D. Riley
openalex   +1 more source

Alkaline–Acid Intestine Environment Controlled by A Carbonic Anhydrase Gene Influences Synthesis of Sex Pheromone by Symbionts

Advanced Science, EarlyView.
A model proposing that elevated rectal expression of CAh1 in males alkalinizes the environment to regulate Bacillus production of a male‐specific sex pheromone. Abstract The intricate interplay between animals and their intestinal microbes is pivotal in shaping various aspects of animal biology.
Shiyu Gui, Lexin Xie, Zhenghao Wang, Yan Chen, Yi Xiao, Ziyun Lin, Jingxiang Chen, Yongyue Lu, Laurent Keller, Daifeng Cheng   +9 more
wiley   +1 more source