Results 51 to 60 of about 19,694 (262)
FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Numerical Analysis of a Fuel Pump for an Aircraft Diesel Engine
MATEC Web of Conferences, 2019 The paper reports on the process of modelling a high-pressure common rail pump designed to supply a two-stroke compression-ignition engine, which includes the presentation of methodology for model construction and results of simulation tests.
Sochaczewski Rafał, Szlachetka Marcin
doaj +1 more source
Applied Sciences, 2018 High-speed, pressure-compensated variable displacement piston pumps are widely used in aircraft hydraulic systems for their high power density. The swash plate is controlled by the pressure-compensated valve, which uses pressure feedback so that the ...
Xu Fang, Xiaoping Ouyang, Huayong Yang
doaj +1 more source
International Journal of Aerospace Engineering, 2022 For the research demand of reusable LOX/kerosene variable thrust liquid rocket engine, a test system with electric displacement pumps is designed and a multidisciplinary modular dynamic simulation method based on AMESim platform is used to analyze the ...
Qingdong Su +5 more
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Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Over Stroke of Carbon Fiber Continuous Sucker Rod
Shiyou jixie, 2019 Carbon fiber continuous sucker rods are used in oil production systems. However, the over stroke was observed in the movement of the plunger with unknown influence, leading to lack of theoretical basis in the design and application of carbon fiber ...
张雷 +5 more
doaj
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Mechanical Engineering Journal, 2015 Hydraulic pumps are positive displacement machines and the primary components of fluid power systems that transform energy from mechanical sources to pressurized oils.
Toshiharu KAZAMA
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A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source