Results 91 to 100 of about 25,228,093 (291)

Cognitive Constructivism in the Development of Medical Education [PDF]

, 2020
This study introduces cognitive constructivism in reference to its emergence in the development of medical education. The main concepts of cognitive constructivism as they relate to knowledge construction and the learner’s process were described, and ...
Korean Medical Education Review (의학교육논단)
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

The spectral model of personal wellbeing and the validity of the Personal Wellbeing Spectral Questionnaire

Frontiers in Psychology
IntroductionPersonal wellbeing is a multidimensional construct encompassing emotional, psychological, social, and spiritual aspects. To capture this complexity, we introduce the Personal Wellbeing Spectrum Theory, which organizes these dimensions into ...
Attila Oláh, Bella Bagdi, Bella Bagdi, András Vargha, András Vargha   +4 more
doaj   +1 more source

Studies of the psychological well-being of low-performing students in US schools [PDF]

Современная зарубежная психология, 2019
The article analyzes the psychological well-being of poorly performing schoolchildren and the personal correlates of academic failure as they are presented in the US school psychology.
Lubovsky D.V.
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Impact of positive self-talk [PDF]

, 2012
x, 106 leaves ; 29 cmOn a daily basis, whether young or old, people are engaged in self-talk. Our thoughts have implications that affect our emotions, motivation and potential accomplishments.
Chopra, Kamal, University of Lethbridge. Faculty of Education   +1 more
core  

Social Cognitive Theory and Medical Education: How Social Interactions Can Inform Learning [PDF]

, 2020
The structures and processes of medical education have changed little since the publication of Flexner’s report, which stressed the scientific orientation of medical education and the curricular structure of 2 years of formal knowledge education and 2 ...
Korean Medical Education Review (의학교육논단)
core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Positive special education: Why are teachers’ and students’ self-efficacy important? Consequences for reading instruction and civic education

This chapter focuses on capability and self-efficacy as one theoretical foundation of positive special education. Beliefs about one’s capabilities are the essence of self-efficacy and departs from social cognitive theory. Self-efficacy refers to people’s
Reichenberg, Monica,
core   +1 more source