Results 111 to 120 of about 5,504,468 (285)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Revisiting the Role of Education for Agricultural Productivity [PDF]

open access: yes
While the majority of micro studies finds that rural education increases agricultural productivity, various recent cross‐country regressions analyzing the determinants of agricultural productivity were only able to detect an insignificant or even ...
Malte Reimers, Stephan Klasen
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CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Financial Education & Account Ownership: Combined Strategy Leads to Better Outcomes [PDF]

open access: yes, 2009
Research from a variety of studies finds that combining financial education and savings account ownership have a positive impact, where each leads a person to seek more of the other.

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Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

School Quality and Family Background in Italy [PDF]

open access: yes
We study if the combined significant reduction in the pupil-teacher ratio and increase in parental education observed in Italy between the end of IIWW and the end of 1980s had a significant impact on the educational attainment and labor market returns of
Daniele Checchi, Giorgio Brunello
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Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Schooling Externalities, Technology and Productivity: Theory and Evidence from U.S. States [PDF]

open access: yes
The recent literature on local schooling externalities in the U.S. is rather mixed: positive external effects of average education levels are hardly to be found but, in contrast, positive externalities from the share of college graduates can often be ...
Giovanni Peri, Susana Iranzo
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Collaborating for Gender Equity in Christian Education

open access: yes, 2020
This essay addresses the importance of teachers promoting gender equity. It explores potential causes for gender discrimination in Christian institutions including double standards, unequal representation, organizational culture and similarity attraction.
Castellon, Adrienne R., Sowerby, Stacy
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