Results 61 to 70 of about 9,753,657 (384)

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Mediating Effects of Positive Thinking and Social Support on Suicide Resilience [PDF]

open access: yes, 2018
Suicide has been the second leading cause of death for 18- to 24-year-olds in the United States since 2011. The stress experienced by undergraduate college students has the potential to increase one’s risk for suicide.
Bekhet, Abir K.   +2 more
core   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Positive Visualization and Its Effects on Strength Training

open access: yesImpulse: The Premier Undergraduate Neuroscience Journal, 2020
The following study examines the effects of positive visualization on strength training. Positive visualization is being defined as: visualizing yourself performing a physical movement to best of your capability or beyond.
Janette Hynes , Zach Turner
doaj  

The Curious Case of Absolute Position Embeddings [PDF]

open access: yesarXiv, 2022
Transformer language models encode the notion of word order using positional information. Most commonly, this positional information is represented by absolute position embeddings (APEs), that are learned from the pretraining data. However, in natural language, it is not absolute position that matters, but relative position, and the extent to which ...
arxiv  

Heritage, health and place:The legacies of local community-based heritage conservation on social wellbeing [PDF]

open access: yes, 2016
Geographies of health challenge researchers to attend to the positive effects of occupying, creating and using all kinds of spaces, including 'green space' and more recently 'blue space'.
Abraham   +32 more
core   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Non-Linear Effects in Asymmetric Reactions: Negative and Positive Stereoselectivity in the Formation of Homoleptic 1:2 Metal to Ligand Complexes of Chiral 1,9-Disubstituted Semicorrin Ligands

open access: yesCHIMIA, 2003
The stereoselectivity of the formation of bis-chelates with the 1,9-disubstituted chiral semicorrin ligands (1S,9S)-dimethyl 5-cyanosemicorrin-1,9-dicarboxylate (1) for Co2+, Ni2+, Cu2+, and Pd2+ and with its (1S,9S)-diethyl analogue 2 for Co2+
Nathalie Guicher   +2 more
doaj   +1 more source

Motivational salience modulates early visual cortex responses across task sets [PDF]

open access: yes, 2017
Motivationally relevant stimuli benefit from strengthened sensory processing. It is unclear, however, if motivational value of positive and negative valence has similar or dissociable effects on early visual processing. Moreover, whether these perceptual
Bayer, Mareike   +5 more
core   +2 more sources

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