Results 101 to 110 of about 45,801 (303)

Advances and Prospects of Stereotactic Radiosurgery and Stereotactic Ablative Body Radiotherapy: Evolving Paradigms in Precision Oncology

open access: yesMed Research, EarlyView.
The graphical abstract outlines the progressive development and impact of stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT). Technological Evolution illustrates the transition from brachytherapy with single‐dose, LDR/HDR schedules to fractionated radiotherapy, three‐dimensional conformal radiotherapy (3DCRT) and Gamma Knife ...
Jing Zhang   +10 more
wiley   +1 more source

Psychiatric Safety of Tirzepatide in People With Obesity and No Known Major Psychopathology: A Post Hoc Analysis of SURMOUNT

open access: yesObesity, EarlyView.
ABSTRACT Objective This post hoc analysis assessed psychiatric changes with tirzepatide in adults with obesity, without known major psychopathology, from SURMOUNT‐1, SURMOUNT‐2, and SURMOUNT‐3. Methods In participants (N = 4056) treated with tirzepatide (5/10/15 mg or maximum tolerated dose 10/15 mg) versus placebo, depressive symptoms and suicidal ...
Thomas A. Wadden   +6 more
wiley   +1 more source

Electrical impedance tomography to evaluate air distribution prior to extubation in very-low-birth-weight infants: a feasibility study

open access: yesClinics, 2013
OBJECTIVES: Nasal continuous positive airway pressure is used as a standard of care after extubation in very-low-birth-weight infants. A pressure of 5 cmH2O is usually applied regardless of individual differences in lung compliance.
Felipe de Souza Rossi   +4 more
doaj  

Age‐Dependent Correlation of Pulmonary Function Impairment and Aortic Arch Stiffness in Mice

open access: yesPediatric Discovery, EarlyView.
This study examined the relationship between aortic arch stiffness and lung function in aging mice. Multiple linear regression modeling showed moderate to strong correlations between the rise in aortic arch stiffness and changes in lung function as the mice progressively aged.
Ayman Isbatan   +10 more
wiley   +1 more source

Optimal Positive End-expiratory Pressure Levels in Tuberculosis-associated Acute Respiratory Distress Syndrome

open access: yesInternational Journal of Mycobacteriology
Background: The objective is to assess lung compliance and identify the optimal positive end-expiratory pressure (PEEP) levels in patients with tuberculosis-associated Acute Respiratory Distress Syndrome (TB-ARDS) compared to non-TB-ARDS patients ...
Seyed MohammadReza Hashemian   +7 more
doaj   +1 more source

Prevalence and Spirometric Transitions of PRISm and Obstruction: A Population‐Based Study

open access: yesRespirology, EarlyView.
ABSTRACT Background and Objective This study aims to assess the prevalence and longitudinal transitions of spirometric patterns defined by the lower limit of normal (LLN) criteria: normal airflow (FEV1/FVC≥LLN, FEV1 ≥ LLN); preserved ratio impaired spirometry (PRISm; FEV1/FVC≥LLN, FEV1 < LLN); or obstruction (FEV1/FVC
Charmaine J. M. Lim   +7 more
wiley   +1 more source

Can Patient Education Lead the Way? Head‐To‐Head Comparison of EXACT and CERT for Early Recognition of Acute COPD Exacerbations

open access: yesRespirology, EarlyView.
Daily head‐to‐head comparison of EXACT vs. CERT for early detection of acute COPD exacerbations. Both tools accurately identified exacerbations at diagnosis (AUC≈0.9), but CERT detected worsening one day earlier (p = 0.006). CERT's simplicity and free access support rapid patient self‐monitoring and may enable timely intervention.
Rainer Gloeckl   +9 more
wiley   +1 more source

Prognostic Value of a Cardiopulmonary Exercise Testing‐Derived Summed Score in Idiopathic Pulmonary Fibrosis and Connective Tissue Disease‐Associated Interstitial Lung Disease: A Prospective Cohort Study

open access: yesRespirology, EarlyView.
A cardiopulmonary exercise testing‐derived summed score effectively predicted mortality or lung transplantation risk in newly diagnosed interstitial lung disease. Higher summed scores (2–5) were associated with markedly lower event‐free survival rates.
Yu‐Lin Tsai   +6 more
wiley   +1 more source

Safety of flow-controlled ventilation with positive and negative end-expiratory pressure in a swine model of intracranial hypertension

open access: yesIntensive Care Medicine Experimental
Background Patients with brain damage often require mechanical ventilation. Although lung-protective ventilation is recommended, the application of increased positive end-expiratory pressure (PEEP) has been associated with elevated intracranial pressure (
Álmos Schranc   +6 more
doaj   +1 more source

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