Results 121 to 130 of about 75,231 (260)

Shear Wave Elastography to Assess Respiratory Muscle Function in Congenital Myopathies

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Respiratory muscle dysfunction is prevalent in congenital myopathies and often leads to respiratory failure. Ultrasound shear wave elastography (SWE) measures tissue elasticity and has been proposed as an alternative to invasive measures of respiratory muscle contractility.
J. L. M. van Doorn, D. Jans, C. L. de Korte, B. G. M. van Engelen, N. C. Voermans, N. van Alfen, C. A. C. Ottenheijm, D. Bachasson, J. Doorduin   +8 more
wiley   +1 more source

Asynchrony Related to Mechanical Ventilation Exacerbates Diaphragm Dysfunction in a Mouse Model of Duchenne Muscular Dystrophy

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims In dystrophic mice (mdx, a genetic homolog of Duchenne muscular dystrophy: DMD), previous studies showed that mechanical ventilation (MV) induces ventilator‐induced diaphragmatic dysfunction (VIDD). However, susceptibility to mechanical stress caused by asynchrony remains unknown.
Mohamad Yehya, Haikel Dridi, Eric Estève, Johan Moreau, Steven Reiken, Andrew R. Marks, Alain Lacampagne, Stefan Matecki   +7 more
wiley   +1 more source

Electrical impedance tomography to evaluate air distribution prior to extubation in very-low-birth-weight infants: a feasibility study

Clinics, 2013
OBJECTIVES: Nasal continuous positive airway pressure is used as a standard of care after extubation in very-low-birth-weight infants. A pressure of 5 cmH2O is usually applied regardless of individual differences in lung compliance.
Felipe de Souza Rossi, Ana Cristina Zanon Yagui, Luciana Branco Haddad, Alice D'Agostini Deutsch, Celso Moura Rebello   +4 more
doaj  

Novel Therapeutics for Chronic Obstructive Pulmonary Disease: From Empirical Bronchodilation to Precision Medicine

Respirology, EarlyView.
ABSTRACT Chronic obstructive pulmonary disease (COPD) remains the third leading cause of death worldwide, and conventional bronchodilator‐based therapies have limited efficacy in preventing exacerbations and disease progression. The 2024–2026 period represents a historic inflection point: three mechanistically distinct agents received Food and Drug ...
Naoya Fujino, Hisatoshi Sugiura
wiley   +1 more source

Determinants of Improved Dyspnea and Exercise Tolerance With Nasal High‐Flow O2 Therapy in Fibrotic Interstitial Lung Disease: A Pilot Physiological Study

Respirology, EarlyView.
We tested the respective effect of high‐flow and supplemental O2 from nasal high‐flow O2 therapy (NHFO2) on dyspnea and exercise tolerance in fibrotic interstitial lung disease. Supplemental O2 and NHFO2 (but not high‐flow) provided improvements in these outcomes at “iso‐O2 saturation” due to reduced ventilatory requirements.
Sarah Thivent, Marylise Ginoux, Samuel Verges, Frédéric Hérengt, Mathieu Marillier   +4 more
wiley   +1 more source

Unveiling the Impact of Digitized Supply Chains on Reducing Food Loss and Waste: A Multiple Case Study of Italian Agri‐Food Firms

Sustainable Development, EarlyView.
ABSTRACT Food loss and waste (FLW) within agri‐food supply chains significantly impact the consumer economy, depleting natural resources and contributing to greenhouse gas emissions, thereby posing a critical challenge to sustainable development. Digital transformation is increasingly recognised as a key lever for reducing FLW in agri‐food supply ...
Stefano Abbate, Piera Centobelli
wiley   +1 more source

Optimal Positive End-expiratory Pressure Levels in Tuberculosis-associated Acute Respiratory Distress Syndrome

International Journal of Mycobacteriology
Background: The objective is to assess lung compliance and identify the optimal positive end-expiratory pressure (PEEP) levels in patients with tuberculosis-associated Acute Respiratory Distress Syndrome (TB-ARDS) compared to non-TB-ARDS patients ...
Seyed MohammadReza Hashemian, Batoul Khoundabi, Ashkan Bahrami, Hamidreza Jamaati, Mohammad Varahram, Leila Saljoughi, Payam Rahimi, Reza Eshraghi   +7 more
doaj   +1 more source

Regulated versus unregulated competition: How drug shortages boost illegal pharmacy sales

Strategic Management Journal, EarlyView.
Abstract Research Summary This study examines how product shortages among legal firms create competitive opportunities for illegal firms. We analyze 713 drug shortages in the United States between 2017 and 2023 and show that shortages substantially increase illicit pharmacies’ sales of affected drugs, which rise by 40.5% during shortages and remain 32 ...
Luis Diestre, Benjamin Barber IV
wiley   +1 more source

Forgoing Nuclear: Nuclear Power Plant Closures and Carbon Emissions in the United States

Southern Economic Journal, EarlyView.
ABSTRACT This paper examines the effect of nuclear power plant decommissioning on electricity generation and carbon emissions in the United States. Using data on nuclear reactor closures in the United States between 1993 and 2022 and data on state‐level carbon emissions and electricity generation from the Energy Information Administration (EIA), this ...
Luke Petach
wiley   +1 more source

Safety of flow-controlled ventilation with positive and negative end-expiratory pressure in a swine model of intracranial hypertension

Intensive Care Medicine Experimental
Background Patients with brain damage often require mechanical ventilation. Although lung-protective ventilation is recommended, the application of increased positive end-expiratory pressure (PEEP) has been associated with elevated intracranial pressure (
Álmos Schranc, John Daniels, Roberta Südy, Fabienne Fontao, Philippe Bijlenga, Guillaume Plourde, Hervé Quintard   +6 more
doaj   +1 more source