Results 51 to 60 of about 572,073 (301)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Environmental and Climate Technologies, 2021 Positive Energy District (PED) is a relatively new concept from which many projects are planned, however, only a few cases are currently close to be materialized, therefore, in this study the PED projects in operation and in implementation process in ...
Rueda Castellanos Sofia, Oregi Xabat
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Sustainable Development of Energy, Water and Environmental Systems and Smart Energy Systems
International Journal of Sustainable Energy Planning and Management, 2022 This 34th volume of the International Journal of Sustainable Energy Planning and Management includes papers from the 2021 conference on Sustainable Development of Energy, Water and Environmental Systems (SDEWES) held October 10-15, 2021, in Dubrovnik ...
Poul Alberg Østergaard +3 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Latest Developments in 4th generation district heating and smart energy systems
International Journal of Sustainable Energy Planning and Management, 2021 This editorial introduces the 31st volume of the International Journal of Sustainable Energy Planning and Management. This volume reports some of the latest developments in energy systems analyses of smart energy systems and of district heating as well ...
Poul Alberg Østergaard +3 more
doaj +1 more source
A database for positive energy districts (PED)
Journal of Physics: Conference Series, 2023 Abstract The development of Positive Energy Districts (PEDs) is a complex process that involves the integration of various technologies, stakeholders, and policies. To facilitate this process, a database for PEDs has been developed as a joint effort of COST Action ‘PED-EU-NET’, IEA EBC Annex 83, and JPI Urban Europe.
Beril Alpagut +11 more
openaire +2 more sources
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source