Results 51 to 60 of about 5,703 (300)
A real options approach to renewable electricity generation in the Philippines
Energy, Sustainability and Society, 2018 Background The Philippines is making a significant stride to become energy independent by developing more sustainable sources of energy. However, investment in renewable energy is challenged by competitive oil prices, very high investment cost for ...
Casper Boongaling Agaton, Helmut Karl
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Position Auctions with Externalities and Brand Effects
CoRR, 2014 19 pages.
Patrick Hummel, R. Preston McAfee
openaire +2 more sources
Research on the game of information security investment based on the Gordon-Loeb model
Tongxin xuebao, 2018 In order to study the impacts of externalities of information security investment,the Gordon-Loeb model was extended to a multi-organization game environment.The relationships of the optimal information security investment with vulnerability,potential ...
Qin WANG, Jianming ZHU
doaj +2 more sources
Multiple peer effects in the diffusion of innovations on social networks: a simulation study
Journal of Innovation and Entrepreneurship, 2018 Peer effects in innovation adoption decisions have been extensively studied. However, the underlying mechanisms of peer effects are generally not explicitly accounted for. Gaps in this knowledge could lead to misestimation of peer effects and inefficient
Hang Xiong +2 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
ICT Use and Successful Learning: The Role of the Stock of Human Capital
Mathematics, 2021 Previous empirical studies have found a weak nexus between the use of information and communication technologies (ICT) for learning and students’ outcomes.
Gregorio Gimenez, Luis Vargas-Montoya
doaj +1 more source