Results 81 to 90 of about 7,851,722 (296)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Premessa

, 2011
La premessa introduce gli atti del convegno "La Musica tra conoscere e fare" (Bologna, 16-17 maggio 2008), promosso dall'allora Dipartimento di Musica e Spettacolo (oggi Dipartimento delle Arti) dell'Università di Bologna, in collaborazione con l ...
LA FACE, GIUSEPPINA, SCALFARO, ANNA
core   +1 more source

The Influence of Face Inversion and Spatial Frequency on the Self-Positive Expression Processing Advantage

Frontiers in Psychology, 2018
Previous research has examined the impact of late self-evaluation, ignoring the impact of the early visual coding stage and the extraction of facial identity information and expression information on the self-positive expression processing advantage ...
Yueyang Yin, Yueyang Yin, Yu Yuan, Lin Zhang   +3 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Face-to-face awake intubation in an upright position in severe maxillofacial trauma

Turkish Journal of Emergency Medicine
Abstract: Maxillofacial injury may cause difficulty during airway assessment and management in the emergency setting. Alternative intubation positions and techniques should be considered to ensure patient safety. A 37-year-old male patient arrived at the emergency department with a degloving maxillofacial injury after a high ...
Laurensia Vidya Ayuningtyas, Airi Mutiar, Prananda Surya Airlangga   +2 more
openaire   +3 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Comparison of two respiratory function monitors for newborn mask ventilation: A randomised crossover study using simulation

Resuscitation Plus
Objectives: Respiratory function monitors (RFM) provide objective feedback on respiratory parameters during face mask ventilation. While traditional RFMs display detailed waveforms, newer devices use simplified, colour-coded graphics. We aimed to compare
C.M. Ní Chathasaigh, A.E. Curley, E. O Currain   +2 more
doaj   +1 more source

Determinants of Engagement in Face-to-Face and Online Patient Support Groups

Journal of Medical Internet Research, 2011
BackgroundAlthough peer-to-peer contact might empower patients in various ways, studies show that only a few patients actually engage in support groups.
Van Uden-Kraan, Cornelia F, Drossaert, Constance HC, Taal, Erik, Smit, Willem M, Bernelot Moens, Hein J, Van de Laar, Mart AFJ   +5 more
doaj   +1 more source