Results 101 to 110 of about 6,998,855 (248)

The infinitive and the gerund-participle as complements of verbs of risk [PDF]

open access: yes, 2009
Ce mémoire, puisant à même certains principes de la linguistique cognitive et de la psychomécanique du langage, porte sur la complémentation verbale de l'anglais avec l'infinitif et le gérondif.
Arseneau, Maryse
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Defending the content view of perceptual experience [PDF]

open access: yes, 2013
This thesis is a defense of the Content View on perceptual experience, of the idea that our perceptual experiences represent the world as being a certain way and so have representational content. Three main issues are addressed in this work.
Zucca, Diego
core  

Positive mental health : measurement, relevance and implications [PDF]

open access: yes, 2012
The professionalization of psychology yielded many advantages, but also led to a main focus on psychopathology in mental health care. This thesis investigated an additional positive approach to mental health, focusing on positive feelings and life satisfaction (emotional well-being) and optimal functioning in both individual (psychological well-being ...
openaire   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

SAT-based preimage attacks on SHA-1 [PDF]

open access: yes, 2012
Hash functions are important cryptographic primitives which map arbitrarily long messages to fixed-length message digests in such a way that: (1) it is easy to compute the message digest given a message, while (2) inverting the hashing process (e.g ...
Nossum, Vegard
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Complementation and Meaning of Forbear in 18th and 19th Century British and American English [PDF]

open access: yes, 2013
Tässä tutkimuksessa tarkastellaan muutoksia nykypäivän englannissa jo harvinaiseksi käyneen forbear-verbin komplementaatiossa ja merkityksessä 1710-luvulta 1920-luvulle.
PETERI, VEERA
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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