Results 121 to 130 of about 6,998,855 (248)
ON THE VARIETY OF POSITIVE IMPLICATIVE BCK-ALGEBRAS
Demonstratio Mathematica, 1984 It is shown that for any chain (tree) with smallest element there is exactly one operation which makes it a positive implicative BCK-algebra whose BCK-order coincides with the originally given order.
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Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
Nature, 2011 D. Baker +7 more
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
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Positive and negative implications of the causal illusion
Consciousness and Cognition, 2017 The human cognitive system is fine-tuned to detect patterns in the environment with the aim of predicting important outcomes and, eventually, to optimize behavior. Built under the logic of the least-costly mistake, this system has evolved biases to not overlook any meaningful pattern, even if this means that some false alarms will occur, as in the case
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Insights into a long life without cancer: The case of the bowhead whale
Molecular Oncology, EarlyView.Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Tax implications for new jobs positions
, 2022 Las redes sociales nos conectan con cualquier lugar. Internet nos permite trabajar desde cualquier parte del mundo, revolucionando el sistema moderno y haciendo necesario replantearse el régimen fiscal actual. El objetivo de este trabajo es identificar las profesiones emergentes más populares que están contribuyendo a la transformación social ...
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
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