Results 31 to 40 of about 4,866,842 (156)

Positive psychology in North America

open access: yes, 2021
The chapter, "Positive psychology in North America" was written by Roger Tweed (Douglas College Faculty). (1st Edition). This handbook discusses the latest findings from different fields of positive psychology from a global perspective by providing a ...

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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Positive Energy Districts for People and the Environment

open access: yes
Cities are hubs of economic activity, social interactions, and innovation but face challenges like pollution, overheating, flooding, and health issues that affect quality of life. Transforming cities into self-sufficient, clean energy systems goes beyond
Andreucci, Maria Beatrice   +3 more
core   +4 more sources

Bounded real lemmas for positive descriptor systems [PDF]

open access: yes, 2015
A well known result in the theory of linear positive systems is the existence of positive definite diagonal matrix (PDDM) solutions to some well known linear matrix inequalities (LMIs).
Yan, Xinggang   +3 more
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Bringing coherence to positive psychology: Faith in humanity

open access: yes, 2020
Currently, positive psychology is experiencing problems with coherence, and the field could benefit from more organizing concepts linking disparate findings and researchers within the field. This incoherence can be seen in several domains.

core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The Make-Up, Estrojet, and Positive State concert flier, SEIU Hall, Washington, D.C., August 25, 1996

open access: yes, 1996
An advertising flier promoting a concert by the punk rock bands The Make-Up, Estrojet, and Positive State. The concert occurred on Sunday, August 25, 1996 at the SEIU Hall in Washington, D.C.
Positive Force DC
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