Results 91 to 100 of about 410 (211)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

ANALYSIS OF EFFECTIVENESS OF THRESHOLDING IN PERFUSION ROI DETECTION ON T2-WEIGHTED MR IMAGES WITH ABNORMAL BRAIN ANATOMY

KPI Science News, 2019
Background. The brain perfusion ROI detection being a preliminary step, designed to exclude non-brain tissues from analyzed DSC perfusion MR images. Its accuracy is considered as the key factor for delivering correct results of perfusion data analysis ...
Svitlana M. Alkhimova, Svitlana V. Sliusar   +1 more
doaj   +1 more source

On positive linear maps preserving invertibility

Journal of Functional Analysis, 1984
A positive linear map \(\Phi\) between two \(C^*\)-algebras is a Jordan homomorphism if \(\Phi\) preserves invertibility and the range of \(\Phi\) is a \(C^*\)-algebra. A counterexample is given for the case that the range of \(\Phi\) is not assumed to be a \(C^*\)-algebra; this answers a question raised by \textit{B. Russo} [Proc. Am. Math. Soc.
Choi, M-D., Hadwin, D., Nordgren, E., Radjavi, H., Rosenthal, P.   +4 more
openaire   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Schmidt states and positivity of linear maps

, 2005
Using pure entangled Schmidt states, we show that m-positivity of a map is bounded by the ranks of its negative Kraus matrices. We also give an algebraic condition for a map to be m-positive. We interpret these results in the context of positive maps as entanglement witnesses, and find that only 1-positive maps are needed for testing entanglement.
Kuah, Aik-meng, Sudarshan, E. C. G.
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Gruess inequality for some types of positive linear maps

Journal of Operator Theory, 2015
Assuming a unitarily invariant norm $|||\cdot|||$ is given on a two-sided ideal of bounded linear operators acting on a separable Hilbert space, it induces some unitarily invariant norms $|||\cdot|||$ on matrix algebras $\mathcal{M}_n$ for all finite values of $n$ via $|||A|||=|||A\oplus 0|||$. We show that if $\mathscr{A}$ is a $C^*$-algebra of finite
Matharu, Jagjit Singh, Moslehian, Mohammad Sal   +1 more
openaire   +2 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source