Results 121 to 130 of about 1,333,113 (282)

Measurement of the Full Shape of the Thermal Sunyaev–Zel’dovich Power Spectrum from the South Pole Telescope and Herschel–SPIRE Observations

open access: yesThe Astrophysical Journal Letters
We present a measurement of the full shape of the power spectrum of the thermal Sunyaev–Zel’dovich (tSZ) effect down to arcminute scales using cosmic microwave background (CMB) data from the South Pole Telescope (SPT) over a roughly 100 deg ^2 field. The
S. Raghunathan   +142 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Ti6Al4V-0.72H on the Establishment of Flow Behavior and the Analysis of Hot Processing Maps

open access: yesCrystals
Significant columnar grains usually occur in the metallurgical microstructure of laser additive manufacturing, and plastic deformation introduced into additive manufacturing can significantly refine grain size.
Jian-Hua Sun   +5 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

A novel golden π-ratio scaling chaotification model for securing medical internet of things applications

open access: yesJournal of Engineering and Applied Science
The rapid advancement of the Medical Internet of Things (MIoT) technology has enabled remote monitoring, real-time data exchange, and personalized treatment; however, it has also introduced critical security challenges that demand efficient, robust ...
Mir Nazish, M. Tariq Banday
doaj   +1 more source

Schmidt states and positivity of linear maps

open access: yes, 2005
Using pure entangled Schmidt states, we show that m-positivity of a map is bounded by the ranks of its negative Kraus matrices. We also give an algebraic condition for a map to be m-positive. We interpret these results in the context of positive maps as entanglement witnesses, and find that only 1-positive maps are needed for testing entanglement.
Kuah, Aik-meng, Sudarshan, E. C. G.
openaire   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy