Results 51 to 60 of about 585,417 (307)
DETECTABILITY OF LINEAR DISCRETE TIME LINEAR SYSTEMS DEFINED BY POSITIVE OPERATORS [PDF]
In this paper we extend the notion of detectability, introduced in [1] in connection with stochastic systems, to a more general class of linear discrete time systems defined by positive operators.
V.M. Ungureanu
doaj
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Some properties of the linear positive operators (III)
Not available.
A. Lupaş
doaj +2 more sources
Weakly Ordered A-Commutative Partial Groups of Linear Operators Densely Defined on Hilbert Space [PDF]
The notion of a generalized effect algebra is presented as a generalization of effect algebra for an algebraic description of the structure of the set of all positive linear operators densely defined on a Hilbert space with the usual sum of operators ...
Janda , Jirí
core
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
On the Monotonicity of Positive Linear Operators
The main result of this paper concerns positive linear approximation operators of the so-called Feller type \[ K_n(f,x): =Ef(T_{n,x}) =\int_I f(t)dG_{n,x} (t),\;n\in\mathbb{N}, \] where the random variable \(T_{n,x}\) is the arithmetic mean of identically distributed random variables \(X_{i,x}\), \(I=1, \dots, n\) taking values in an interval \(I\) and
KHAN M. K. +2 more
openaire +3 more sources
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source

