Results 51 to 60 of about 8,449,626 (275)
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
On positive linear operators [PDF]
, 2019 Approximation theory received much attention in the last century, and an intriguing area in this field is positive linear operators. This thesis is a literature survey on positive linear operators.
Jannat, Farzaneh
core
Unbounded Functions and Positive Linear-Operators [PDF]
, 1982 The approximation of unbounded functions by positive linear operators under multiplier enlargement is investigated. It is shown that a very wide class of positive linear operators can be used to approximate functions with arbitrary growth on the real ...
Swetits, J. J. +3 more
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Algebraic reflexivity of isometry groups and automorphism groups of some operator structures [PDF]
, 2013 We establish the algebraic re exivity of three isometry groups of operator structures: The group of all surjective isometries on the unitary group, the group of all surjective isometries on the set of all positive invertible operators equipped with ...
Botelho, Fernanda +2 more
core
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
General estimates for the linear positive operators which preserve linear functions
Journal of Numerical Analysis and Approximation Theory, 1989 Not available.
Radu Păltănea
doaj +2 more sources
Convergence Theorems for Derivatives of a New Baskakov -Type Operators
Wasit Journal for Pure SciencesThe motive of this paper is to introduce and investigate the derivatives of some Baskakov operators. Firstly, we treated with the convergence theorems on some certain type of Baskakov operators and then we found the derivative of these operators.
Haneen Jaafar, haneen jaafar
doaj +1 more source