Results 51 to 60 of about 587,156 (263)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Some properties of the linear positive operators (III)

open access: yesJournal of Numerical Analysis and Approximation Theory, 1974
Not available.
A. Lupaş
doaj   +2 more sources

Asymptotic Behaviour of the Iterates of Positive Linear Operators

open access: yesAbstract and Applied Analysis, 2011
We present a general result concerning the limit of the iterates of positive linear operators acting on continuous functions defined on a compact set.
Ioan Gavrea, Mircea Ivan
doaj   +1 more source

Some Positone Problems Suggested by Nonlinear Heat Generation [PDF]

open access: yes, 1967
There is much current interest in boundary value problems containing positive linear differential operators and monotone functions of the dependent variable, see for example, M.A. Krasnosel'ski [1] and H. H. Schaefer [2]. We call such problems "positone"
Cohen, Donald S., Keller, Herbert B.
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Weakly Ordered A-Commutative Partial Groups of Linear Operators Densely Defined on Hilbert Space [PDF]

open access: yes, 2017
The notion of a generalized effect algebra is presented as a generalization of effect algebra for an algebraic description of the structure of the set of all positive linear operators densely defined on a Hilbert space with the usual sum of operators ...
Janda , Jirí
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

On Geometric Series of Positive Linear Operators

open access: yesConstructive Mathematical Analysis, 2019
We study the existence and the norm of operators obtained as power series of linear positive operators with particularization to Bernstein operators. We also obtain a Voronovskaja-kind theorem.
openaire   +3 more sources

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