Results 81 to 90 of about 221,597 (311)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Completions of positive semidefinite operator matrices
, 2011 This chapter deals with positive definite and semidefinite completions of partial operator matrices. It considers the banded case in Section 2.1, the chordal case in Section 2.2, the Toeplitz case in Section 2.3, and the generalized banded case and the ...
Hugo J. Woerdeman, Mihály Bakonyi
core +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Positive-operator-valued measures: A general setting for frames
, 2013 This chapter presents an overviewof close parallels that exist between the theory of positive-operator-valued measures (POVMs) associated with a separable Hilbert space and the theory of frames on that space, including its most important generalizations.
William Moran (18349080) +2 more
core
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
, 1999 In this paper the authors prove that the generalized positive p selfadjoint (GPpS) operators in Banach space satisfy the generalized Schwarz inequality, solve the maximal dissipative extension representation of p dissipative operators in Banach space by ...
Tian LX +2 more
core +1 more source
Decomposable approximations of nuclear C*-algebras [PDF]
, 2012 We show that nuclear <i>C</i><sup>*</sup>-algebras have a refined version of the completely positive approximation property, in which the maps that approximately factorize through finite dimensional algebras are convex ...
Kirchberg, Eberhard +5 more
core +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Positive Solutions of Fractional Differential Equation with -Laplacian Operator
Abstract and Applied Analysis, 2013 The basic assumption of ecological economics is that resource allocation exists social optimal solution, and the social optimal solution and the optimal solution of enterprises can be complementary.
Teng Ren, Xiaochun Chen
doaj +1 more source