Results 71 to 80 of about 853,515 (301)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Healthy Organizations and the Link to Peaceful Societies: Strategies for Implementing Organizational Change [PDF]

open access: yes, 2002
When designing and implementing an organizational change process, we are intentionally and oftentimes significantly impacting the lives of the human beings who make up the organization.
Coolican, Maria, Jackson, Jeannette
core   +3 more sources

The relationship between core self-assessment and organizational citizenship behavior motivations with organizational citizenship behavior of schools [PDF]

open access: yesPizhūhish/hā-yi rahbarī va mudīriyyat-i āmūzishī, 2015
This study aimed to determine the relationship between core self-assessment and organizational citizenship behavior motivations with organizational citizenship behavior of schools administrators was conducted in three grades of Behbehan city.
کریم سواری
doaj   +1 more source

ANALISIS PENGARUH KOMPENSASI FINANSIAL TERHADAP ORGANIZATIONAL CITIZENSHIP BEHAVIOR (OCB) DENGAN DISIPLIN KERJA DAN MOTIVASI BERPRESTASI SEBAGAI VARIABEL INTERVENING (Studi pada Badan Narkotika Nasional Provinsi Jawa Tengah) [PDF]

open access: yes, 2016
Organizational Citizenship Behavior (OCB) is a behavior that needs to be owned by civil servants. Many ways can be done to improve the Organizational Citizenship Behavior (OCB) one with a financial compensation.
PRASETYA, Sindhi Saraayu   +1 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Organizational Citizenship Behavior and Counterproductive Work Behavior: Cross-cultural comparisons between Turkey and the Netherlands [PDF]

open access: yes, 2010
This research project explores cultural determinants that facilitate positive employee behavior. In the literature, this behavior is identified as organizational citizenship behavior (OCB).
Cem-Ersoy, N. (Nevra)
core  

Correlation Between Organizational Memory and Innovative Work Behavior [PDF]

open access: yes, 2014
This study aims to determine the relationship between organizational memory and innovative work behavior. The study was conducted on 100 employees from various levels and positions in a company that produce and trade electronic solar equipment.
Etikariena, A. (Arum), Muluk, H. (Hamdi)
core   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

The Relationship between Positive Organizational Behavior with Job Satisfaction, Organizational Citizenship Behavior, and Employee Engagement

open access: yesInternational Business Research, 2015
The concept of positive organizational behavior (POB) was introduced several years ago as a way to create competitive advantage. Therefore, organizations pay more attention to Positive Organizational Behavior due to the changing and competitive nature of organizations.
Zahra Pouramini, Marjan Fayyazi
openaire   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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