Results 121 to 130 of about 5,058,316 (286)

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Parenting behaviors over time and their effects on cortical and limbic brain structure in children and young adults

Developmental Cognitive Neuroscience
Parenting behaviors significantly impact children's development, including maturation of emotion regulation skills and associated brain regions (e.g., amygdala, hippocampus, prefrontal cortex).
Mirjam Habegger, Plamina Dimanova, Réka Borbás, Elena Federici, Denis Ribeaud, Manuel P. Eisner, Todd A. Hare, Nora Maria Raschle   +7 more
doaj   +1 more source

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li, Dong‐Lin Liang, Li‐Ping Gao, Wei‐Wei Zhang, Wei Zhou, A. Ruhan, Bing Xu, Run‐Dong Cao, Kang Xiao, Cao Chen, Qi Shi, Xiao‐Ping Dong   +11 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

The efficacy of positive parenting training and parenting based on mentalization on improving the mother-child relationship [PDF]

مجله علوم روانشناختی
Background: The mother-child relationship is considered one of the important factors in a child’s development. So far, various training methods have been implemented to improve the mother-child relationship, but no study has compared two commonly used ...
Narges Ataran, Mohammad Mozafari, Reza Ghorban Jahromi, Sajad Amini Manesh   +3 more
doaj  

Mediating role of self-control in the association between perceived parenting attitudes and smartphone addiction among middle school students

Discover Psychology
This study aimed to examine the association of perceived parenting attitudes with smartphone addiction among adolescents, focusing on self-control’s mediating role. A survey assessing positive and negative perceived parenting attitudes, self-control, and
Youngmi Kwon, Miae Kim, Hyorim Lee
doaj   +1 more source

Divorce by the positive - parents help parents

INFAD, 2018
Increasingly, in Occidentalized societies, divorce is a growing reality and Portugal in not an exception. This family transition as increased the divorce rates in the last two decades, with along with some worrying indicators of educational and psychosocial nature, which, among other thematic realities derived from the families, have led to a demand ...
openaire   +1 more source

Positive about parents [PDF]

, 2009
Paper presented to the Scottish Institute for Residential Child Care Annual Conference, 2009: 'Seeing the whole picture: working in partnership to enhance the lives of children looked after away from home'
Pilkington, Kevin, Burns, Claire
openaire   +1 more source

Integrating Time‐Adjusted Imaging Instability Into Functional Outcome Prediction After Intracerebral Hemorrhage: Development and Validation of the HAGIV Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song, Ren Ke, Anqi Chen, Yufei Fu, Hang Zhou, Rujia Wang, Liwei Zou, Yongqiang Yu, Ming Yuan, Xiaoming Qiu, Mengzhou Xue   +10 more
wiley   +1 more source