Results 251 to 260 of about 327,787 (287)

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

Advanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong, Lina Duan, Jie Xiao, Yulu Deng, Hongxia Wang, Yajie Zhang, Xiumei Hu, Haifang Wang, Taixue An, Xin Li, Yurong Qiu, Lei Zheng, Haixia Li   +12 more
wiley   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source

Selective Targeting of Tip Endothelial Cells as a Therapeutic Strategy for Tumor Angiogenesis

Advanced Science, EarlyView.
Doppel protein is selectively expressed in tip endothelial cells within the tumor vasculature, where it promotes tip cell motility and stabilizes the tip cell phenotype. Targeting Doppel with monoclonal antibodies disrupts this stabilization, impairs angiogenic sprouting, and reduces tumor angiogenesis, offering a selective and druggable switch for ...
Byoungmo Kim, Ha Kyeong Lee, Zulfikar Azam, Jeong Uk Choi, Riajul Wahab, Na Kyeong Lee, Yoon Gun Ko, So‐Young Choi, Se‐Ra Lee, Wan Seob Shim, Taeeung Kim, In‐San Kim, Farzana Alam, Sang Yoon Kim, Seong Who Kim, Youngro Byun, Taslim A Al‐Hilal   +16 more
wiley   +1 more source

Parenting Early Intervention Programme Evaluation (Research report DFE-RR121(a)) [PDF]

, 2011
Band, Sue, Barlow, Jane, Conlon, Gavan, Cullen, Mairi Ann, Cullen, Stephen, Davis, Hilton, Evans, Ray, Lindsay, Geoff, Strand, Steve   +8 more
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Promoting positive parenting

2012
Contents: Series Foreword: Monographs in Parenting. Preface. F. Juffer, M.J. Bakermans-Kranenburg, M.H. van IJzendoorn, Promoting Positive Parenting: An Introduction. F. Juffer, M.J. Bakermans-Kranenburg, M.H. van IJzendoorn, Methods of the Video-Feedback to Promote Positive Parenting Alone, With Sensitive Discipline, and With Representational ...
Femmie Juffer, Marian J. Bakermans-Kranenburg, Marinus H. van IJzendoorn   +2 more
openaire   +2 more sources

Positive parenting

Nursing Standard, 2012
A programme of intensive support for teenage mothers and their babies, delivered by nurses, is being rolled out across Scotland. Developed in the United States, there is evidence that the Family Nurse Partnership improves the health and life chances of families, but there is concern that the jobs may draw scarce health visiting staff away from other ...
openaire   +3 more sources

Positive Parenting: Parent Involvement

1989
The Parent Involvement construct assessed the number of activities the boy does with his parent(s) and the amount of time they spend together. Two of the four indicators were based on the Family Activities Checklist (Patterson, 1982); one indicator was for the parents and one was for the child. The two additional indicators were both child self-report,
Deborah M. Capaldi, Gerald R. Patterson
openaire   +1 more source

Positive Parenting: Positive Reinforcement

1989
The Positive Reinforcement construct focused on the extent to which the parents show appreciation for good behavior from the son. There were seven indicators assessing this construct: observer impressions of the parent, parent interview, interviewer impressions, child interview, parent telephone interview, and two closely related microsocial variables,
Deborah M. Capaldi, Gerald R. Patterson
openaire   +1 more source

Positive parenting.

Nursing forum, 2015
While parenting has been researched and explored in both the professional and public realms, elements of the current key constructs involving the positive parenting of a child are still missing. The aim of this article is to define the concept of positive or "good" parenting to further extend research toward child health promotion knowledge across ...
Andrea, Seay, Wyona M, Freysteinson, Judith, McFarlane   +2 more
openaire   +1 more source

Economic Pressure, Parent Positivity, Positive Parenting, and Child Social Competence

Journal of Child and Family Studies, 2019
The current study examined how economic pressure impacts parental positivity and positive parenting separately for mothers and fathers, as well as how positivity and parenting impact child social competence. This study included 207 mothers, fathers, and their first-born child from toddlerhood through the preschool years.
Shinyoung Jeon, Tricia K. Neppl
openaire   +1 more source