Results 101 to 110 of about 8,509,903 (292)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Dynamic Behavior of a Delayed Model with One Core Enterprise and Four Satellite Enterprises

open access: yesAppliedMath
In this paper, an economic competition–cooperation model is examined, which has one core enterprise and four satellite enterprises. This extends previous smaller models in the literature mathematically.
Chunhua Feng
doaj   +1 more source

Existence, uniqueness and stability of solutions to a delay hematopoiesis model

open access: yesJournal of Innovative Applied Mathematics and Computational Sciences, 2022
This work aims to investigate a delay hematopoiesis model where the delay depends on both the time and the current density of mature blood cells. Based on the Banach contraction principle, the Schauder's fixed point theorem and some properties of a ...
Ahlème Bouakkaz, Rabah Khemis
doaj  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Existence and global asymptotic stability of positive periodic solutions of a Lotka-Volterra type competition systems with delays and feedback controls

open access: yesElectronic Journal of Differential Equations, 2013
The existence of positive periodic solutions of a periodic Lotka-Volterra type competition system with delays and feedback controls is studied by applying the continuation theorem of coincidence degree theory.
Anh Tuan Trinh
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Comparing one-shot and multi-shot methods for solving periodic of Riccati differential equations [PDF]

open access: yes, 2007
- One-shot methods and recently proposed multi-shot methods for computing stabilizing solutions of continuoustime periodic Riccati differential equations are examined and evaluated on two test problems.
Varga, Andreas   +2 more
core  

Positive periodic solution for a neutral delay competitive system [PDF]

open access: yes, 2004
In this paper we study the existence of positive periodic solutions for a class of neutral type competitive system with delay. Applying the continuation theorem of coincidence degree theory, a general criteria on the existence of positive periodic ...
Liu, Zhijun, Zhijun Liu
core   +1 more source

Dynamics of a Nonautonomous Leslie-Gower Type Food Chain Model with Delays

open access: yesDiscrete Dynamics in Nature and Society, 2011
A nonautonomous Leslie-Gower type food chain model with time delays is investigated. It is proved the general nonautonomous system is permanent and globally asymptotically stable under some appropriate conditions.
Hongying Lu, Weiguo Wang
doaj   +1 more source

Home - About - Disclaimer - Privacy