Results 161 to 170 of about 11,536,029 (288)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Sensitivity and positive predictive value of diagnosis codes for acute kidney injury in Denmark. [PDF]

Clin Kidney J
Høyer S, Heide-Jørgensen U, Jensen SK, Pottegård A, Christiansen CF.   +4 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

International classification of diseases codes have low positive predictive value for neonatal morbidities. [PDF]

J Perinatol
Hendrickson JE, Birch RJ, Sola-Visner MC, Branchford BR, Chen X, Custer BS, Desimone RA, Bougie DW, Edwards EM, Goel R, Gottschall J, Hod EA, Moayeri M, Roubinian NH, Karam O, Stone EF, Luban NLC, Josephson CD, Patel RM, REDS-IV-P.   +19 more
europepmc   +1 more source

The Sign RCA Models: Comparing Predictive Accuracy of VaR Measures [PDF]

Evaluating Value at Risk (VaR) methods of predictive accuracy in an objective and effective framework is important for both efficient capital allocation and loss prediction.
Joanna Górka
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Indication-stratified histopathological yield and positive predictive value of sonographic and hysteroscopic impressions in women undergoing hysteroscopy: A 1551-case tertiary center cohort study. [PDF]

Medicine (Baltimore)
Namli ME, Kurt Güven H, Bostanci Durmuş A, Bahadir Ş, Tunç F, Yavuz B, Yilmaz E.   +6 more
europepmc   +1 more source

The Positive Predictive Value of Pediatric Stroke Diagnoses in Administrative Data: A Retrospective Validation Study. [PDF]

Clin Epidemiol, 2023
Bindslev JB, Johnsen SP, Hansen K, Valentin JB, Hoei-Hansen CE, Truelsen T.   +5 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Positive Predictive Value of Tissue Transglutaminase IgA for Celiac Disease. [PDF]

Pediatrics
Chang D, Wong M, Camila Cardenas M, Stahl MG, Liu E, Caplan M, Gidrewicz D, King JA, Turner JM, Leonard MM, Lee D, Cristina Pacheco M, Dickerson J, Raber C, Badalyan V, Chugh A, Setty M, Baek C, Singh A, Fahey L, Walsh CM, Silvester JA, Absah I.   +22 more
europepmc   +1 more source