Results 171 to 180 of about 11,536,029 (288)

Positive Predictive Value of ICD-10 Codes to Identify Acute Suicidal and Self Harm Behaviors. [PDF]

Hosp Pediatr, 2023
Johnson JA, Williams DJ, Feinstein JA, Grijalva CG, Zhu Y, Dickinson E, Stassun JC, Sekmen M, Tanguturi YC, Gay JC, Antoon JW.   +10 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Real-World Positive Predictive Value and False Positive Rates of Laboratory-Based HIV Antigen/Antibody Testing by Age and Sex-United States, 2019-2024. [PDF]

J Acquir Immune Defic Syndr
Zhu W, Bessler P, Lale A, Delaney K, O'Shea J, Huang YA, Kourtis AP, Hoover KW.   +7 more
europepmc   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Clinical and Imaging Factors Impacting Positive Predictive Value of Prostate MRI. [PDF]

Radiology
Soerensen SJC, Rosenberg J, Franks Z, Rusu M, Fan RE, Sonn GA, Ghanouni P.   +6 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Applying the "positive predictive value-recall diagram" to monitor performance and provide recommendations for screening radiologists. [PDF]

Eur Radiol
Geertse TD, Tetteroo E, Smid-Geirnaerdt MJA, Duijm LEM, Pijnappel RM, van der Waal D, Broeders MJM.   +6 more
europepmc   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Feline leukemia virus point-of-care lateral flow tests have low positive predictive value in apparently healthy shelter cats. [PDF]

Front Vet Sci
Urig HE, Woodruff KA, Brookshire WC, Smith DR.   +3 more
europepmc   +1 more source

Positive predictive value of noninvasive prenatal testing for sex chromosome abnormalities. [PDF]

Mol Biol Rep, 2022
Guo N, Cai M, Lin M, Xue H, Huang H, Xu L.   +5 more
europepmc   +1 more source