Results 171 to 180 of about 3,799,305 (383)

Long-term predictive value of the Framingham Risk Score for Stroke in HIV-positive vs HIV-negative men [PDF]

, 2013
Farrah J. Mateen, Wendy S. Post, Ned Sacktor, Alison G. Abraham, James T. Becker, Bryan Smith, Roger Detels, Eileen Martin, John Phair, Russell T. Shinohara   +9 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Minimizing signal detection time in postmarket sequential analysis: balancing positive predictive value and sensitivity

, 2014
Judith C. Maro, Jeffrey S. Brown, Gerald J. Dal Pan, Martin Kulldorff   +3 more
openalex   +2 more sources

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

The Value of Bacterial Culture During Clean Orthopedic Surgery a Prospective Study of 1,036 Patients [PDF]

, 2017
Objective: To determine whether bacterial cultures of the wounds of patients undergoing clean orthopedic surgery would help predict infection. Methods: During 1 year, 1,256 cultures were performed for 1,102 patients who underwent clean orthopedic surgery.
Bernard, Louis, Hoffmeyer, Pierre, Lew, Daniel, Monin, Daniel, Rohner, Peter, Sadowski, Christophe, Stern, Richard, Wyssa, Blaise   +7 more
core  

The Positive Predictive Value of Pediatric Stroke Diagnoses in Administrative Data: A Retrospective Validation Study. [PDF]

Clin Epidemiol, 2023
Bindslev JB, Johnsen SP, Hansen K, Valentin JB, Hoei-Hansen CE, Truelsen T.   +5 more
europepmc   +1 more source

14P Assessing the predictive value of HER2DX pCR-score for pathologic complete response (pCR) in early-stage HER2-positive (HER2+) breast cancer (BC) under real-world conditions [PDF]

O. Martínez-Sáez, M. Marin, L. Pare Brunet, G. Villacampa Javierre, A. Vivancos, María Vidal, B. Adamo, Raquel Gómez Bravo, I. Garcia Fructuoso, T. Pascual, N. Chic, Pedro Jesús Rodríguez de Rivera, F. Schettini, E. Seguí Solís, B. Conte, P. Villagrasa Gonzalez, E. Sanfeliu Torres, Fara Brasó‐Maristany, A. Prat, Montserrat Muñoz-Mateu   +19 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Valor de la resonancia magnética en el diagnóstico de las lesiones de rodilla [PDF]

, 1996
Para determinar la eficacia diagnóstica de la resonancia magnética en las lesiones de la rodilla se han estudiado 60 pacientes tomando como referencia los hallazgos obtenidos en la artroscopia.
Bosch Reig, Vicente, López Casquero, C., Villanueva García, E.   +2 more
core  

Positive Predictive Value of ICD-10 Codes to Identify Acute Suicidal and Self Harm Behaviors. [PDF]

Hosp Pediatr, 2023
Johnson JA, Williams DJ, Feinstein JA, Grijalva CG, Zhu Y, Dickinson E, Stassun JC, Sekmen M, Tanguturi YC, Gay JC, Antoon JW.   +10 more
europepmc   +1 more source