Results 101 to 110 of about 318,952 (348)

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

open access: yesAdvanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao   +36 more
wiley   +1 more source

The negative and positive pressure system of natural balanced ventilation

open access: yesTechnical Transactions, 2020
This paper discusses the results of research conducted with the Ansys Fluent programme on the air flow through natural ventilation supply and exhaust ducts of rooms located on the ground and upper floor of a building. A scenario with air inflow to a room
Gaczoł Tomasz
doaj   +1 more source

Absolute electrical impedance tomography (aEIT) guided ventilation therapy in critical care patients: simulations and future trends [PDF]

open access: yes, 2010
Thoracic electrical impedance tomography (EIT) is a noninvasive, radiation-free monitoring technique whose aim is to reconstruct a cross-sectional image of the internal spatial distribution of conductivity from electrical measurements made by injecting ...
Brown, B.H.   +5 more
core   +2 more sources

A Modular Vaccine Platform Against SARS‐CoV‐2 Based on Self‐Assembled Protein Nanoparticles

open access: yesAdvanced Science, EarlyView.
A modular BP26 nanoparticle vaccine platform incorporating the SpyTag/SpyCatcher system enables high‐density, repetitive antigen display with post‐expression flexibility. Conjugation of the SARS‐CoV‐2 RBD to BP26 nanoparticles elicits strong humoral immunity and confers protection against viral challenge in vivo.
Seojung Lee   +6 more
wiley   +1 more source

A Comparison between Nasal Intermittent Positive Pressure Ventilation and Nasal Continuous Positive Airway Pressure Ventilation in the Treatment of Neonatal Respiratory Distress Syndrome [PDF]

open access: yesIranian Journal of Neonatology, 2015
Background: Nasal intermittent positive pressure ventilation (NIPPV) is a non-invasive ventilatory mode, which delivers mechanical ventilation via nasal tubes or prongs.
Ahmad Shah Farhat   +3 more
doaj  

Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho‐Epithelial Cells by Modulating Eicosanoid Lipid Signaling

open access: yesAdvanced Science, EarlyView.
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta   +14 more
wiley   +1 more source

Positive Pressure Ventilation

open access: yes
Potchileev I, Doroshenko M, Mohammed AN.
europepmc   +2 more sources

H⁺ Exchange‐Driven ppb‐Level and High‐Selective Formaldehyde Detection at Room Temperature for Environmental and Clinical Applications

open access: yesAdvanced Science, EarlyView.
This article presents an innovative room‐temperature formaldehyde sensor based on H⁺ exchange method, achieving ppb‐level detection limit and exceptional selectivity. The study highlights its practical potential for real‐time environmental monitoring and clinical diagnostic applications.
Lubing Cai   +9 more
wiley   +1 more source

Ventilation and cave air PCO2 in the Bunker-Emst Cave System (NW Germany): implications for speleothem proxy data [PDF]

open access: yes, 2019
Cave air pCO2 (carbon dioxide partial pressure) is, along with drip rate, one of the most important factors controlling speleothem carbonate precipitation.
Breitenbach, Sebastian   +4 more
core   +2 more sources

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

open access: yesAdvanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang   +7 more
wiley   +1 more source

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