Results 121 to 130 of about 578,949 (401)
This study describes the creation of injectable Brachyury (Bry) mRNA‐loaded Fucoidan‐functionalized GelMA hydrogel microspheres (BLNP@GF). These microspheres efficiently suppress inflammation, enhance extracellular matrix (ECM) synthesis in degenerated nucleus pulposus cells, and mitigate intervertebral disc degeneration (IVDD) in rat models.
Yuhao Gong+12 more
wiley +1 more source
A fresh look at paralytics in the critically ill: real promise and real concern. [PDF]
Neuromuscular blocking agents (NMBAs), or "paralytics," often are deployed in the sickest patients in the intensive care unit (ICU) when usual care fails.
Kenyon, Nicholas J+2 more
core +2 more sources
Neonatal drug depression and respiratory distress managed by positive pressure ventilation and exchange transfusion. [PDF]
Julie Young, Suhair Moayid Rasheed
openalex +1 more source
The study in this paper found that activating the α2A receptors of astrocytes in the thoracic spinal cord can reduce the release of inflammatory factors, thereby decreasing the necroptosis of GABAergic neurons and consequently alleviating myocardial injury caused by sepsis.
Ruilin He+9 more
wiley +1 more source
Current respiratory management for Acute Respiratory Distress Syndrome [PDF]
Acute Respiratory Distress Syndrome still high has a mortality rate. There are many causes for respiratory failure including sepsis, aspiration, pneumonia, pancreatitis, chest trauma, transfusion, and so on.
中根 正樹+6 more
core +1 more source
Developing Biomaterial‐Based mRNA Delivery System for Lung Disease Treatment
Schematic illustration of biomaterial delivery mRNA for the treatment of lung diseases. Abstract Lung disease remains a persistent global health challenge. Advances in medical research have led to innovative strategies to combat these conditions, with biomaterials emerging as a promising platform for targeted drug delivery.
Qiancheng Gu+7 more
wiley +1 more source
High-intensity non-invasive positive pressure ventilation for stable hypercapnic COPD
Background: The objective of the present analysis is to describe the outcomes of high-intensity non-invasive positive pressure ventilation (NPPV) aimed at maximally decreasing PaCO2 as an alternative to conventional NPPV with lower ventilator settings in
Wolfram Windisch, Moritz Haenel, Jan H Storre, Michael Dreher
doaj
Positive expiratory pressure plateau: improved gas exchange during mechanical ventilation [PDF]
R. W. McIntyre+2 more
openalex +1 more source
Engineered neutrophil‐derived vesicles (SOD2‐Fer‐1@CVs) co‐delivering antioxidant and ferroptosis‐inhibitory agents enable inflammation‐targeted, ROS‐responsive therapy for ischemia–reperfusion injury in lung transplantation. Synergizing with ex vivo lung perfusion, this strategy alleviates oxidative stress and inflammation, restores vascular integrity,
Hao‐Xiang Yuan+10 more
wiley +1 more source
Intermittent positive pressure ventilation in the treatment of severe crushing injuries of the chest. [PDF]
M. Ambiavagar+3 more
openalex +1 more source