Results 91 to 100 of about 8,109,340 (304)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

On positive sequences of reals whose block sequence has an asymptotic distribution function [PDF]

Notes on Number Theory and Discrete Mathematics
In this paper we study the properties of the unbounded sequence 0≤y₁≤y₂≤y₃≤... of positive reals having asymptotic distribution function of the form x^λ.
József Bukor, Ferdinánd Filip, János T. Tóth   +2 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Existence of multiple solutions for quasilinear elliptic equations in R^N

Electronic Journal of Differential Equations, 2014
In this article, we establish the multiplicity of positive weak solution for the quasilinear elliptic equation $$\displaylines{ -\Delta_p u+\lambda|u|^{p-2}u=f(x) |u|^{s-2 }u+h(x)|u|^{r-2}u\quad x\in \mathbb{R}^N,\cr u>0\quad x\in \mathbb{R}^N ...
Honghui Yin, Zuodong Yang
doaj  

Infinitely divisible positive definite sequences [PDF]

Transactions of the American Mathematical Society, 1969
Introduction. Sequences of complex numbers which generate positive semidefinite Toeplitz or Hankel matrices occur naturally in many areas of mathematics and are usually called positive definite sequences. It is well known that a sequence formed from a positive integer power of the terms of a positive definite sequence is always itself a positive ...
openaire   +2 more sources

On the Positivity Problem for Simple Linear Recurrence Sequences, [PDF]

, 2014
Given a linear recurrence sequence (LRS) over the integers, the Positivity Problem} asks whether all terms of the sequence are positive. We show that, for simple LRS (those whose characteristic polynomial has no repeated roots) of order 9 or less, Positivity is decidable, with complexity in the Counting Hierarchy.
Joël Ouaknine, James Worrell 0001
openaire   +2 more sources

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

MOSAL : software tools for multiobjective sequence alignment [PDF]

, 2014
Multiobjective sequence alignment brings the advantage of providing a set of alignments that represent the trade-off between performing insertion/deletions and matching symbols from both sequences. Each of these alignments provide a potential explanation
Monsanto Pinheiro, Miguel, Maryam Abbasi, Luís LuísPaquete, Paquete, Luís, Pedro Matias, Luís Paquete, Abbasi, Maryam, Miguel Pinheiro, Matias, Pedro   +8 more
core   +1 more source

Nature-Positive Solutions and CGIAR: A pop up exhibit

Nature-Positive Solutions and CGIAR is a pop-up art exhibition featuring information artworks produced in collaboration with The Lexicon of Sustainability and the CGIAR Nature-Positive Solutions Initiative.
CGIAR Nature-Positive Solutions Initiative, Lexicon of Sustainability   +1 more
core   +1 more source

An Analog of Multiplier Sequences for the Set of Totally Positive Sequences

Zurnal matematiceskoj fiziki, analiza, geometrii
A real sequence $(b_k)_{k=0}^\infty$ is called totally positive if all minors of the infinite matrix $ \left\| b_{j-i} \right\|_{i, j =0}^\infty$ are nonnegative (here $b_k=0$ for $k<0$). In this paper, we investigate the problem of description of the set of sequences $(a_k)_{k=0}^\infty$ such that for every totally positive sequence $(b_k)_{k=0 ...
Katkova, Olga, Vishnyakova, Anna
openaire   +2 more sources