Results 101 to 110 of about 17,909,648 (352)
, 2011 The method of upper and lower solutions and the Schauder fixed point theorem are used to investigate the existence and uniqueness of a positive solution to a singular boundary value problem for a class of nonlinear fractional differential equations with ...
Changyou Wang +3 more
semanticscholar +1 more source
Positive solutions to sublinear elliptic problems
Colloquium Mathematicum, 2019 Let $L$ be a second order elliptic operator $L$ with smooth coefficients defined on a domain $ $ in $\mathbb{R}^d $, $d\geq3$, such that $L1\leq 0$. We study existence and properties of continuous solutions to the following problem \begin{equation}\label{00} Lu= (\cdot,u),% & \hbox{in $ $; in the sens of distribution;} \\ \end{equation} in $ ,$
openaire +3 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Nonexistence of positive solution for an integral equation on a Half-Space R+n
, 2011 Let $n, m$ be a positive integer and let $R_+^n$ be the $n$-dimensional upper half Euclidean space. In this paper, we study the following integral equation \begin{eqnarray} u(x)=\int_{R_+^n}G(x,y)u^pdy, \end{eqnarray} where \begin{eqnarray*} G(x ...
Yanqin Fang, Jihui Zhang
semanticscholar +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
On the number of positive solutions of nonlinear systems
Journal of Mathematical Analysis and Applications, 2003 This paper is devoted to the existence, multiplicity and nonexistence of positive solutions to boundary value problems on \([0,1]\) for a class of second-order differential systems where the main common operator is the one-dimensional \(p\)-Laplacian, \(p> 1\). The author uses a fixed-point theorem in a cone due to \textit{M. A.
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Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Positive Solutions for a Hadamard Fractional p-Laplacian Three-Point Boundary Value Problem [PDF]
, 2019 Jiqiang Jiang +3 more
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
On the positive, “radial” solutions of a semilinear elliptic equation in N$\mathbb {H}^N$ [PDF]
, 2012 Catherine Bandle, Yoshitsugu Kabeya
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