Results 101 to 110 of about 5,764,328 (311)

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Existence and asymptotic behaviour of positive solutions for semilinear elliptic systems in the Euclidean plane

open access: yesElectronic Journal of Differential Equations, 2011
We study the semilinear elliptic system $$ Delta u=lambda p(x)f(v),Delta v=lambda q(x)g(u), $$ in an unbounded domain D in $ mathbb{R}^2$ with compact boundary subject to some Dirichlet conditions.
Abdeljabbar Ghanmi, Faten Toumi
doaj  

Positive solutions of Schrodinger-Poisson systems with Hardy potential and indefinite nonlinearity

open access: yesElectronic Journal of Differential Equations, 2020
In this article, we study the nonlinear Schrodinger-Poisson system $$\displaylines{ -\Delta u+u-\mu\frac{u}{|x|^2}+l(x) \phi u=k(x)|u|^{p-2}u \quad x\in\mathbb{R}^3, \cr -\Delta\phi=l(x)u^2 \quad x\in\mathbb{R}^3, }$$ where $k\in C(\mathbb{R}^3 ...
Yongyi Lan, Biyun Tang, Xian Hu
doaj  

Existence of a positive solution for nonlinear Schrödinger equations with general nonlinearity

open access: yesAdvances in Nonlinear Analysis, 2014
We study the following nonlinear Schrödinger equations: -Δu+V(x)u=f(u)inℝN.$ - \Delta u + V(x) u = f(u) \quad \text{in } {\mathbb {R}^N}. $ The purpose of this paper is to establish the existence of a positive solution under general conditions which are ...
Sato Yohei, Shibata Masataka
doaj   +1 more source

Positive solutions for superlinear elliptic equations

open access: yesJournal of Mathematical Analysis and Applications, 2003
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

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