Results 121 to 130 of about 1,950,635 (268)

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

A necessary and sufficient condition for the existence of positive solutions to singular boundary-value problems of higher order differential equations

open access: yesElectronic Journal of Differential Equations, 2006
By constructing some special cones and using fixed point theorem of cone expansion and compression, this paper presents some necessary and sufficient conditions for the existence of $C^{4n-2}$ positive solutions to a class of singular boundary-value
Chenglong Zhao   +2 more
doaj  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Three positive solutions for a system of singular generalized Lidstone problems

open access: yesElectronic Journal of Differential Equations, 2009
In this article, we show the existence of at least three positive solutions for the system of singular generalized Lidstone boundary value problems $displaylines{ (-1)^m x^{(2m)}=a(t)f_1(t,x,-x'',dots,(-1)^{m-1}x^{(2m-2)},y,-y'',cr dots,(-1)^{n-1}y^{
Jiafa Xu, Zhilin Yang
doaj  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Multiple positive solutions to mixed boundary value problems for singular ordinary differential equations on the whole line

open access: yesNonlinear Analysis, 2012
This paper is concerned with the mixed boundary value problem of the second order singular ordinary differential equation    [Φ(ρ(t)x 0 (t))]0 + f(t, x(t), x0 (t)) = 0, t ∈ R, limt→−∞ x(t) = R +∞ −∞ g(s, x(s), x0 (s)) ds, limt→+∞ ρ(t)x 0 (t) = R +∞
Yuji Yuji
doaj  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Positive solutions to boundary-value problems of p-Laplacian fractional differential equations with a parameter in the boundary

open access: yesElectronic Journal of Differential Equations, 2012
In this article, we consider the following boundary-value problem of nonlinear fractional differential equation with $p$-Laplacian operator $$displaylines{ D_{0+}^eta(phi_p(D_{0+}^alpha u(t)))+a(t)f(u)=0, quad 0<t<1, cr u(0)=gamma u(xi)+lambda,
Zhenlai Han   +3 more
doaj  

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