Results 131 to 140 of about 10,534,085 (253)

Positive solutions to boundary-value problems of p-Laplacian fractional differential equations with a parameter in the boundary

Electronic Journal of Differential Equations, 2012
In this article, we consider the following boundary-value problem of nonlinear fractional differential equation with $p$-Laplacian operator $$displaylines{ D_{0+}^eta(phi_p(D_{0+}^alpha u(t)))+a(t)f(u)=0, quad 0<t<1, cr u(0)=gamma u(xi)+lambda,
Zhenlai Han, Hongling Lu, Shurong Sun, Dianwu Yang   +3 more
doaj  

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Global continuum and multiple positive solutions to a p-Laplacian boundary-value problem

Electronic Journal of Differential Equations, 2012
A p-Laplacian boundary-value problem with positive nonlinearity is considered. The existence of a continuum of positive solutions emanating from $(lambda,u)=(0,0)$ is shown, and it can be extended to $lambda=infty$.
Chan-Gyun Kim, Junping Shi
doaj  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Existence and global attractivity of the unique positive periodic solution for discrete hematopoiesis model

, 2015
In this paper, a discrete Hematopoiesis model is studied. By using fixed point theorem of decreasing operator, we obtain sufficient conditions for the existence of unique positive periodic solution. Particularly,we give iterative sequence which converges
Yao, Zhijian
core  

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Comparative Evaluation of En Bloc Staining Protocols for Deep-Learning Segmentation of Dorsal Root Ganglia in SBF-SEM. [PDF]

J Imaging
Borisovs V, Bossi M, Matino L, Marmiroli P, Cavaletti G.   +4 more
europepmc   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Associations of solution building and resilience with school refusal behavior among elementary school students. [PDF]

PLoS One
Yoshida T, Wakashima K, Takagi G, Sakuraba M, Jordan SS, Sakamoto K, Haruyama R.   +6 more
europepmc   +1 more source