Results 101 to 110 of about 2,039,640 (315)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Asymptotically linear and superlinear elliptic equations with gradient terms

open access: yesElectronic Journal of Differential Equations, 2020
In this article we establish the existence of solutions for elliptic problem involving a gradient term. To handle the so-called non-variational problem, we use a variational methods. We assume that the nonlinear term satisfies an asymptotically linear
Yuanhong Wei, Jian Tian
doaj  

Existence and iteration of a positive solution to a second‐order quasilinear problem

open access: yesMathematical Modelling and Analysis, 2010
A successive iteration sequence of positive solution is structured for a singular second‐order quasilinear problem. The sequence can converge uniformly to the positive solution of the problem.
Qingliu Yao
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Positive Periodic Solution for Second-Order Singular Semipositone Differential Equations [PDF]

open access: yes, 2013
We study the existence of a positive periodic solution for second-order singular semipositone differential equation by a nonlinear alternative principle of Leray-Schauder.
Xiumei Xing, Xiumei Xing
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Positive solutions to sublinear elliptic problems

open access: yesColloquium Mathematicum, 2019
Let $L$ be a second order elliptic operator $L$ with smooth coefficients defined on a domain $Ω$ in $\mathbb{R}^d $, $d\geq3$, such that $L1\leq 0$. We study existence and properties of continuous solutions to the following problem \begin{equation}\label{00} Lu=φ(\cdot,u),% & \hbox{in $Ω$; in the sens of distribution;} \\ \end{equation} in $Ω ...
openaire   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Positive Solution of Singular Fractional Differential Equation in Banach Space [PDF]

open access: yes, 2011
We investigated a singular multipoint boundary value problem for fractional differential equation in Banach space. The nonlinear term (,,) is positive and singular at = and (or) =.
Haibo Chen, Jianxin Cao
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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