Results 101 to 110 of about 10,534,085 (253)

Positive Almost Periodic Solution on a Nonlinear Differential Equation

open access: yes, 2011
We study the following nonlinear equationdx(t)/dt=x(t)[a(t)-b(t)xα(t)-f(t,x(t))]+g(t), by using fixed point theorem, the sufficient conditions of the existence of a unique positive almost periodic solution for above system are obtained, by using the ...
Tian Li-xin, Ni Hua, Liu Xun
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Semilinear elliptic problems involving Hardy-Sobolev-Maz'ya potential and Hardy-Sobolev critical exponents

open access: yesElectronic Journal of Differential Equations, 2016
In this article, we study a class of semilinear elliptic equations involving Hardy-Sobolev critical exponents and Hardy-Sobolev-Maz'ya potential in a bounded domain. We obtain the existence of positive solutions using the Mountain Pass Lemma.
Rui-Ting Jiang, Chun-Lei Tang
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Varying domains in a general class of sublinear elliptic problems

open access: yesElectronic Journal of Differential Equations, 2004
In this paper we use the linear theory developed in [8] and [9] to show the continuous dependence of the positive solutions of a general class of sublinear elliptic boundary value problems of mixed type with respect to the underlying domain.
Santiago Cano-Casanova   +1 more
doaj  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Positive solutions for a 2nth-order p-Laplacian boundary value problem involving all derivatives

open access: yesElectronic Journal of Differential Equations, 2013
In this work, we are mainly concerned with the positive solutions for the 2nth-order p-Laplacian boundary-value problem $$displaylines{ -(((-1)^{n-1}x^{(2n-1)})^{p-1})' =f(t,x,x',ldots,(-1)^{n-1}x^{(2n-2)},(-1)^{n-1}x^{(2n-1)}),cr x^{(2i)}(0)=x ...
Youzheng Ding, Jiafa Xu, Xiaoyan Zhang
doaj  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Uniqueness of positive solutions for a fractional differential equation via a fixed point theorem of a sum operator

open access: yesElectronic Journal of Differential Equations, 2012
In this work, we study the existence and uniqueness of positive solutions for nonlinear fractional differential equation boundary-value problems. Our analysis relies on a fixed point theorem of a sum operator. Our results guarantee the existence of a
Chen Yang, Chengbo Zhai
doaj  

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