Results 161 to 170 of about 17,909,648 (352)
Balanced implicit Patankar–Euler methods for positive solutions of stochastic differential equations of biological regulatory systems [PDF]
Aimin Chen +5 more
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Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Another understanding of fourth-order four-point boundary-value problems
Electronic Journal of Differential Equations, 2008 In this article we investigate the existence of positive and/or negative solutions of a classes of four-point boundary-value problems for fourth-order ordinary differential equations.
Petio S. Kelevedjiev +2 more
doaj
On Existence of Symmetric Positive Solutions for SSBVPs on Time Scales
, 2021 Cansel KUYUMCU, Erbil Çetin
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Existence of positive periodic solutions for first-order nonlinear differential equations with multiple time-varying delays [PDF]
, 2022 Xiaoling Han, Ceyu Lei
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Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
BLOW UP OF SOLUTIONS WITH POSITIVE INITIAL ENERGY FOR THE NONLOCAL SEMILINEAR HEAT EQUATION [PDF]
, 2012 Zhong Bo Fang, Lu Sun
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Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source