Results 161 to 170 of about 2,039,640 (315)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Techniques for power system simulation using multiple processors [PDF]
, 1990 The thesis describes development work which was undertaken to improve the speed of a real-time power system simulator used for the development and testing of control schemes.
Taylor, Alistair James Eden
core
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Analytical Solution for the Loss Distribution of a Collateralized Loan under a Quadratic Gaussian Default Intensity Process [PDF]
In this study, we derive an analytical solution for expected loss and the higher moment of the discounted loss distribution for a collateralized loan. To ensure nonnegative values for intensity and interest rate, we assume a quadratic Gaussian process ...
Satoshi Yamashita, Toshinao Yoshiba
core
Positive Periodic Solution for Second-Order Singular Semipositone Differential Equations
, 2020 We study the existence of a positive periodic solution for second-order singular semipositone differential equation by a nonlinear alternative principle of Leray-Schauder.
Xiumei Xing
core
Electronic Journal of Differential Equations, 2006 By constructing some special cones and using fixed point theorem of cone expansion and compression, this paper presents some necessary and sufficient conditions for the existence of $C^{4n-2}$ positive solutions to a class of singular boundary-value
Chenglong Zhao +2 more
doaj
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Three positive solutions for a system of singular generalized Lidstone problems
Electronic Journal of Differential Equations, 2009 In this article, we show the existence of at least three positive solutions for the system of singular generalized Lidstone boundary value problems $displaylines{ (-1)^m x^{(2m)}=a(t)f_1(t,x,-x'',dots,(-1)^{m-1}x^{(2m-2)},y,-y'',cr dots,(-1)^{n-1}y^{
Jiafa Xu, Zhilin Yang
doaj