Results 171 to 180 of about 13,879,944 (380)
Bounds on positive integral solutions of linear Diophantine equations [PDF]
I. Borosh, L. B. Treybig
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The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang+3 more
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Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou+11 more
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Uniqueness and multiplicity of positive radial solutions to the super-critical Brezis-Nirenberg problem in an annulus [PDF]
The super-critical Brezis-Nirenberg problem in an annulus is considered. The new uniqueness result of positive radial solutions is established for the three-dimensional case. It is also proved that the problem has at least three positive radial solutions when the inner radius of the annulus is sufficiently small and the outer inner radius of the ...
arxiv
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa+13 more
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Principal solutions of positive linear Hamiltonian systems [PDF]
Don Hinton
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Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu+7 more
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A Solution of Indoor Positioning System
This paper describes the use of ultra broadband indoor location technology within the area of the unified all personnel and equipment in planning, scheduling solution, realize the full view of the systematic monitoring sites, coherent continuous tracking and track the extraction.
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KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock+10 more
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On the positive solutions of boundary-value problems for a class of nonlinear differential equations
Charles V. Coffman
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