Results 171 to 180 of about 17,377,748 (367)

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Three positive solutions for a system of singular generalized Lidstone problems

Electronic Journal of Differential Equations, 2009
In this article, we show the existence of at least three positive solutions for the system of singular generalized Lidstone boundary value problems $displaylines{ (-1)^m x^{(2m)}=a(t)f_1(t,x,-x'',dots,(-1)^{m-1}x^{(2m-2)},y,-y'',cr dots,(-1)^{n-1}y^{
Jiafa Xu, Zhilin Yang
doaj  

On the positive solutions of boundary-value problems for a class of nonlinear differential equations

, 1967
Charles V. Coffman
openalex   +1 more source

Positive solutions and spectral properties of second order elliptic operators [PDF]

, 1981
W. Allegretto
openalex   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Positive Solutions for a nonlinear n-th order m-point boundary-value problem

Electronic Journal of Differential Equations, 2011
Using the Leggett-Williams fixed point theorem in cones, we prove the existence of at least three positive solutions to the nonlinear $n$-th order $m$-point boundary-value problem $$displaylines{ Delta^{n}u(k)+a(k)f(k,u)=0, quad kin {0,N},cr u(0)=0,
Jiehua Zhang, Yanping Guo, Yude Ji
doaj  

Representation theorems for positive solutions of parabolic equations [PDF]

, 1988
Yehuda Pinchover
openalex   +1 more source

Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?

Molecular Oncology, EarlyView.
 
Chen‐xi Li, Zhong‐cheng Gong
wiley   +1 more source

Positive solutions to boundary-value problems of p-Laplacian fractional differential equations with a parameter in the boundary

Electronic Journal of Differential Equations, 2012
In this article, we consider the following boundary-value problem of nonlinear fractional differential equation with $p$-Laplacian operator $$displaylines{ D_{0+}^eta(phi_p(D_{0+}^alpha u(t)))+a(t)f(u)=0, quad 0<t<1, cr u(0)=gamma u(xi)+lambda,
Zhenlai Han, Hongling Lu, Shurong Sun, Dianwu Yang   +3 more
doaj  

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source