Results 81 to 90 of about 5,619,071 (301)
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Positive solutions for multipoint boundary-value problem with parameters
Electronic Journal of Differential Equations, 2008 In this paper, we study a generalized Sturm-Liouville boundary-value problems with two positive parameters. By constructing a completely continuous operator and combining fixed point index theorem and some properties of the eigenvalues of linear ...
Zhongli Wei, Juanjuan Xu
doaj
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Positive solutions of a boundary value problem with integral boundary conditions
Electronic Journal of Differential Equations, 2011 We consider boundary-value problems studied in a recent paper. We show that some existing theory developed by Webb and Infante applies to this problem and we use the known theory to show how to find improved estimates on parameters $mu^*, lambda ...
Jeff R. L. Webb
doaj
Positive solutions for nonvariational Robin problems
Asymptotic Analysis, 2018 We study a nonlinear Robin problem driven by the p-Laplacian and with a reaction term depending on the gradient (convection term). Using the theory of nonlinear operators of monotone-type and the asymptotic analysis of a suitable perturbation of the original equation, we show the existence of a positive smooth solution.
Papageorgiou, Nikolaos S. +2 more
openaire +5 more sources
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
FEBS Letters, EarlyView.This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
FEBS Letters, EarlyView.Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
On the uniqueness of positive solution of an elliptic equation
Applied Mathematics Letters, 2005 Ministerio de Ciencia y ...
Delgado Delgado, Manuel +1 more
openaire +3 more sources
FEBS Letters, EarlyView.Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
Positive solutions of elliptic equations [PDF]
Pacific Journal of Mathematics, 1978 Moss, William F., Piepenbrink, John
openaire +4 more sources