Results 81 to 90 of about 5,764,328 (311)

Positive solutions for multipoint boundary-value problem with parameters

open access: yesElectronic Journal of Differential Equations, 2008
In this paper, we study a generalized Sturm-Liouville boundary-value problems with two positive parameters. By constructing a completely continuous operator and combining fixed point index theorem and some properties of the eigenvalues of linear ...
Zhongli Wei, Juanjuan Xu
doaj  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Positive solutions of the diophantine equation

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1981
Integral solutions of x3 + λy + 1 − xyz = 0 are observed for all integral λ. For λ = 2 the 13 solutions of the equation in positive integers are determined. Solutions of the equation in positive integers were previously determined for the case λ = 1.
openaire   +3 more sources

Positive solutions of elliptic nonpositone problems

open access: yesDifferential and Integral Equations, 1992
The authors give conditions for the existence or nonexistence of positive solutions of second order subcritical elliptic nonpositone problems. No assumption is made that the problems be radial nor that they possess a variational structure.
W. Allegretto   +2 more
openaire   +5 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy