Results 121 to 130 of about 3,843,324 (325)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Multiplicity of positive solutions for a class of nonlinear Schrödinger equations [PDF]
, 2010 Claudianor O. Alves +1 more
openalex +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Positive solutions for nonlinear Robin problems
Electronic Journal of Differential Equations, 2017 We consider a parametric Robin problem driven by the p-Laplacian with an indefinite potential and with a superlinear reaction term which does not satisfy the Ambrosetti-Rabinowitz condition. We look for positive solutions.
Diego Averna +2 more
doaj
Positive solutions of viscoelastic problems
, 2009 23 pp, 2 ...
Seredynska, Malgorzata, Hanyga, Andrzej
openaire +2 more sources
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Positive solutions for nonlinear elliptic systems
Electronic Journal of Differential Equations, 2012 In this article, we study the existence of positive solutions for the system $$displaylines{ Delta u=H(x,u,v),cr Delta v=K(x,u,v),hbox{in }mathbb{R}^n; (ngeq 3), }$$ where $H,K: mathbb{R}^nimes[0,infty)imes[0,infty)o[0,infty)$ are continuous ...
Adel Ben Dekhil
doaj
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source