Results 131 to 140 of about 457,753 (313)

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller, Lauren N. Coffey, Shelley R. H. Mockler, Katie M. Laubscher, Carrie M. Stephan, M. Bridget Zimmerman, Katherine D. Mathews   +6 more
wiley   +1 more source

The shooting method and positive solutions of fourth-order impulsive differential equations with multi-strip integral boundary conditions [PDF]

, 2018
Yuke Zhu, Huihui Pang
openalex   +1 more source

Existence of positive solutions of some integral equations

, 2004
Summary: We study the existence of positive solutions of the integral equation \[ x(t)= \int^1_0k(t,s)f\bigl(s,x(s),x'(s),\dots,x^{(n-1)}(s)\bigr)\,ds,\;n \geq 2 \] in both \(C^{n-1}[0,1]\) and \(W^{n-1,p}[0,1]\) spaces, where \(p \geq 1\). The Krasnoselskiĭ fixed point theorem on cone is used.
openaire   +3 more sources

Existence of positive solutions for a nonlinear quadratic integral equation

Electronic Journal of Differential Equations, 2019
The authors study the existence of positive solutions for the nonlinear quadratic integral equation of the form \[x(t) = g(t, x(t))\int_{-\infty}^t a(t,t-s)f(s,x(s))\;ds,\;t\in\mathbb{R},\] where \(f, g, a\) satisfy some conditions. They prove the existence and uniqueness of bounded and continuous solution with positive infimum by using fixed point ...
Chu-Hang Wang, Hui-Sheng Ding, Gaston M. N'Guerekata   +2 more
openaire   +2 more sources

Positive Solutions of a Hammerstein Integral Equation with a Singular Nonlinear Term, II

Journal of Integral Equations and Applications, 2000
The author presents the existence of a positive measurable solution of a Hammerstein equation of the first kind with a singular nonlinear term at the origin. In section 1 the assumptions and the two theorems obtained are stated. Sections 2, 3 and 4 contain the demonstration and proof of the theorems. Sections 5 and 6 are dedicated to Appendices 1 and 2.
openaire   +6 more sources

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source

Positive Stepanov-like almost automorphic solutions for systems of nonlinear delay integral equations

Electronic Journal of Differential Equations, 2021
Abdellatif Sadrati, Abderrahim Zertiti
doaj  

Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas, Mauro Monforte, Angel Sanchez‐Montañez, Penélope Romero‐Duque, Elena Pegoraro, Jordi Díaz‐Manera, Dmitry Vlodavets, Lorenzo Maggi, Marco Moscatelli, Adele D‘Amico, Montse Olivé, Jorge Alonso‐Pérez, Giacomo Comi, José Miguel Escudero‐Fernández, Gabriela S. Urcuyo, Anna Pichiecchio, Angela Berardinelli, Kristl G. Claeys, Claudio Bruno, Chiara Panicucci, Sara Bortolani, Eleonora Torchia, Enzo Ricci, Soledad Monges, Jorge A. Bevilacqua, Jorge Diaz‐Jara, Maggie C. Walter, Simone Thiele, Nicoline Løkken, John Vissing, Susana Quijano‐Roy, Robert Y. Carlier, Nicol C. Voermans, Chiara Marini‐Bettolo, Michela Guglieri, Volker Straub, Lea Leonardis, Francina Munell, David Gómez‐Andrés, Giorgio Tasca   +39 more
wiley   +1 more source

Oscillation of solutions to delay differential equations with positive and negative coefficients

Electronic Journal of Differential Equations, 2000
In this article we present infinite-integral conditions for the oscillation of all solutions of first-order delay differential equations with positive and negative coefficients.
El M. Elabbasy, A. S. Hegazi, Samir H. Saker   +2 more
doaj