Results 101 to 110 of about 214,966 (272)

Assessing urban renewal opportunities by combining 3D building information and geographic big data

Geo-spatial Information Science
The assessment of urban renewal (UR) potential aims to prioritize areas for UR, which are essential for sustainable urban revitalization. However, conventional data sources often fall short in encompassing diverse urban characteristics in the evaluation ...
Xin Zhao, Nan Xia, ManChun Li
doaj   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

EUCLIDEAN MINIMUM SPANNING-TREES AND BICHROMATIC CLOSEST PAIRS

, 1991
We present an algorithm to compute a Euclidean minimum spanning tree of a given set S of N points in E(d) in time O(T(d)(N, N) log(d) N), where T(d)(n, m) is the time required to compute a bichromatic closest pair among n red and m green points in E(d ...
Cheong, Otfried, AGARWAL, PK, WELZL, E, EDELSBRUNNER, H   +3 more
core   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Cutaneous adverse events with antibody-drug conjugates: a FAERS-based pharmacovigilance study

Frontiers in Medicine
IntroductionAntibody-drug conjugates (ADCs) have revolutionized oncology by integrating the target specificity of monoclonal antibodies with the potency of cytotoxic payloads.
Huiwen Sun, Jinhan Chen, Qian Xu, Chen Chen, Jinsheng Yu, Qijin Shu   +5 more
doaj   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Two Comments on Minimum Spanning Trees

, 1998
Minimum spanning trees in graphs are well-studied objects. In this note we want to share our observations of two of their properties which we believe are not as well known as others.
David Kravitz
core  

Prediction of total iodine dose of I-131 therapy for Graves’ hyperthyroidism achieved remission status: a random forest regressor model approach to assess treatment efficacy

Frontiers in Endocrinology
ObjectiveGraves’ hyperthyroidism (GH) presents significant challenges in optimizing Iodine-131 (I-131) therapy, largely due to the variability in patient responses and the limitations of traditional dosing methods.
Lu Lu, Dongyun Meng, Xiaojuan Wei, Yan Chen, Shaozhou Mo, Zeyong Sun, Fengyang Song, Yuehua Li, Kehua Liao, Wentan Huang   +9 more
doaj   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

The P-Value for Cost Sharing in Minimum Cost Spanning Tree Situations

The aim of this paper is to introduce and axiomatically characterize the P-value as a rule to solve the cost sharing problem in minimum cost spanning tree (mcst) situations.The P-value is related to the Kruskal algorithm for finding an mcst.Moreover, the
Moretti, S., Brânzei, R., Tijs, S.H., Norde, H.W.   +3 more
core