Results 81 to 90 of about 214,966 (272)
An improved algorithm for the k-source maximum eccentricity spanning trees
Let G=(V,E,w) be an undirected graph with positive edge lengths and S⊂V a set of k specified sources. The k-source maximum eccentricity spanning tree is a spanning tree T minimizing the maximum distance from a source to a vertex, i.e., maxs∈S{maxv∈V{dT(s,
Ye Wu, Bang
core +1 more source
Running is one of the most popular sports practiced today and biomechanical variables are fundamental to understanding it. The main objectives of this study are to describe kinetic, kinematic, and spatiotemporal variables measured using four inertial ...
Álvaro Pareja-Cano +3 more
doaj +1 more source
INFLUENCE OF CAPITAL FLIGHT ON BUDGET IMPLEMENTATION IN NIGERIA [PDF]
The subject of budgeting in Nigeria has been a yearly affair which though good in content, but without an appreciable result. Consequently, this study examined the effect of capital flight on budget implementation in Nigeria.
Kingsley Onyekachi ONYELE +1 more
doaj
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Minimum Face-Spanning Subgraphs of Plane Graphs (Extended Abstract)
. A plane graph is a planar graph with a fixed embedding. Let G = (V, E) be an edge weighted connected plane graph, where V and E are the set of vertices and edges, respectively. Let F be the set of faces of G.
Ali Patwary +2 more
core
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source

