Results 131 to 140 of about 88,651 (261)

A 3D Bioprinted Spheroid‐Laden dECM‐Enriched Osteosarcoma Model for Enhanced Drug Testing and Therapeutic Discovery

Advanced Healthcare Materials, EarlyView.
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues, Maria Catarina Carreira, Mafalda S. Santos, Daniela Pacheco, Frederico Castelo Ferreira, Paola Sanjuan‐Alberte, João Carlos Silva   +6 more
wiley   +1 more source

Understanding the Effects of Conductive Polymer Electrode Coating on Recorded Neural Signals

Advanced Healthcare Materials, EarlyView.
Conductive polymer coatings are widely explored to improve the quality of signals recorded with chronically implanted neural electrodes, offering enhanced biocompatibility along with reduced electrode impedance. Combining computational modelling and data from PEDOT:PTS coated and PtIr electrodes in rats, we show that improvements in signal quality with
Karthik Sridhar, Judith Evers, Alexandre Trotier, Manus Biggs, Madeleine M. Lowery   +4 more
wiley   +1 more source

Histology-specific Prognostic Impact of Microscopic Positive Surgical Margins in Renal Cell Carcinoma: Implications for Postoperative Surveillance. [PDF]

Eur Urol Open Sci
Musso G, Meagher MF, Dabbas M, Garofano G, Birouty N, Yuen KL, Baker B, Saitta C, Patil D, Saito K, Yasuda Y, Tanaka H, Montorsi F, Briganti A, Salonia A, Capitanio U, Larcher A, Rosiello G, Fujii Y, Master VA, Derweesh IH.   +20 more
europepmc   +1 more source

Clinical outcomes for men with positive surgical margins after radical prostatectomy-results from the South Australian Prostate Cancer Clinical Outcomes Collaborative community-based registry. [PDF]

Asian J Urol, 2023
Beckmann KR, O'Callaghan ME, Vincent AD, Moretti KL, Brook NR.   +4 more
europepmc   +1 more source

Hybrid Nanofibers for Multimodal Accelerated Wound Healing

Advanced Healthcare Materials, EarlyView.
Fabrication of wound healing scaffolds based on biocompatible nanofibers. Nanofibers offering high surface area, flexibility, and biocompatibility significantly improved the healing outcome in vivo. Histological, immunological, and anti‐inflammatory markers are noticeably better in treated wounds.
Viraj P. Nirwan, Bence Bajusz, Norbert Fabók, Marina Rudan Dimlic, Jelena Budimir, Tshepang Mqatywa, Miklós Gyöngy, Márton Ferencz, Dorottya Kocsis, Olexandr Bondarenko, Mariia Rolduhina, Milena Lengyel, Istvan Antal, Rebecca Hengsbach, Franciska Erdő, Amir Fahmi   +15 more
wiley   +1 more source

The outcomes of partial nephrectomy - considerations that contribute to positive surgical margins. [PDF]

Rom J Morphol Embryol
Iordache A, Mareş NA, Iordache N, Berdan MG, Mardare M, Puşcaşu AI, Geavlete BF, Georgescu DA, Petca RC, Jinga V, Ginghină O, Blidaru A.   +11 more
europepmc   +1 more source

A multi-surgeon learning curve analysis of overall and site-specific positive surgical margins after RARP and implications for training. [PDF]

J Robot Surg, 2022
Gandi C, Totaro A, Bientinesi R, Marino F, Pierconti F, Martini M, Russo A, Racioppi M, Bassi P, Sacco E.   +9 more
europepmc   +1 more source

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

Advanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni, Gretel S. Major, Sam Arnold, Samuel Tomkins, Eugenia Spessot, Scott Loeffler, Kieran Lau, Richard Tan, Jessica Harte, Roslyn Kemp, Tess Reynolds, Jelena Rnjak‐Kovacina, Gary J. Hooper, Tim B. F. Woodfield, David C. Kieser, Khoon S. Lim   +15 more
wiley   +1 more source

3D-printed model for resection of positive surgical margins in robot-assisted prostatectomy. [PDF]

BJU Int
Engesser C, Brantner P, Gahl B, Walter M, Gehweiler J, Seifert H, Subotic S, Rentsch C, Wetterauer C, Bubendorf L, Vlajnic T, Hosseini A, Ebbing J.   +12 more
europepmc   +1 more source

Positive surgical margins may not affect the survival of patients with renal cell carcinoma after partial nephrectomy: A meta-analysis based on 39 studies. [PDF]

Front Oncol, 2022
Bai R, Gao L, Wang J, Jiang Q.
europepmc   +1 more source