Results 71 to 80 of about 6,094,300 (289)

Prediction of Positive Surgical Margins in Sinonasal Tract Squamous Cell Carcinoma

, 2016
Background: In patients with clinical T4 (cT4) squamous cell carcinoma (SCC) of sinonasal tract who received surgery, the relationship between positive surgical margins and positive clinical N stage as diagnosed by the presence of cervical lymph node ...
Hasegawa Yasuhisa, Yasuhisa Hasegawa, Hitoshi Hirakawa, Yasushi Yatabe, Taijiro Ozawa, Nobuhiro Hanai, Yujiro Fukuda, Hidenori Suzuki, Hiroshi Yamashita, Eiichi Sasaki   +9 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Is the ≥1 cm Width of the Resection Margin in Benign and Borderline Phyllodes Tumor Necessary to Reduce Recurrence?

The Breast Journal
Background. Phyllodes tumors (PTs) are fibroepithelial neoplasms of the breast, with current treatment guidelines recommending wide excision to achieve surgical margins of ≥1 cm to minimize the recurrence risk.
Nattakarn Changchit, Natthawadee Laokulrath, Pradit Rushatamukayanunt, Pongthep Pisarnturakit   +3 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Robot-assisted radical prostatectomy in the treatment of patients with clinically high-risk localized and locally advanced prostate cancer: single surgeons functional and oncologic outcomes

BMC Urology, 2022
Background Optimal treatment approaches for high-risk localized and locally advanced prostate cancer remain controversial and there are currently no standard treatments.
Tae Young Shin, Yong Seong Lee
doaj   +1 more source

Significance and management of positive surgical margins at the time of radical prostatectomy

Indian Journal of Urology, 2014
Positive surgical margins (PSM) at the time of radical prostatectomy (RP) result in an increased risk of biochemical recurrence (BCR) and secondary treatment. We review current literature with a focus on stratifying the characteristics of the PSM that may define its significance, the impact of modern imaging and surgical approaches in avoidance of PSM,
Jonathan L. Silberstein, James A. Eastham   +1 more
openaire   +3 more sources

Positive Surgical Margins at Partial Nephrectomy: Predictors and Oncological Outcomes [PDF]

Journal of Urology, 2008
The prognostic significance and optimal management of positive surgical margins following partial nephrectomy remain ill-defined. We combine data from 2 tertiary care intuitions, and report predictors of positive surgical margins and long-term oncological outcomes for patients with positive surgical margins.Clinical, pathological and followup data on 1,
Ofer, Yossepowitch, R Houston, Thompson, Bradley C, Leibovich, Scott E, Eggener, Joseph A, Pettus, Eugene D, Kwon, Harry W, Herr, Michael L, Blute, Paul, Russo   +8 more
openaire   +2 more sources

Systematic Review of Studies Reporting Positive Surgical Margins After Bladder Neck Sparing Radical Prostatectomy [PDF]

, 2017
Bladder neck preservation (BNP) during radical prostatectomy (RP) has been proposed as a method to improve early recovery of urinary continence after radical prostatectomy.
Hamdy, FC, Alastair D. Lamb, Hamdy, Freddie, Leslie, T, Bell, RW, Lamb, Alastair, Clare Verrill, Lamb, AD, Verrill, Clare, Richard W. Bell, Freddie C. Hamdy, Bellangino, M, Mariangela Bellangino, Verrill, C, Tom Leslie   +14 more
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Defining Clinically Meaningful Positive Surgical Margins in Patients Undergoing Radical Prostatectomy for Localised Prostate Cancer

, 2021
The impact of positive surgical margins (PSMs) on the risk of metastases in prostate cancer (PCa) patients treated with radical prostatectomy (RP) is still ...
Mazzone, Elio, Fossati, Nicola, Scarcella, Simone, Scuderi, Simone, Briganti, Alberto, Montorsi, Francesco, Gandaglia, Giorgio, Stabile, Armando, Robesti, Daniele, Mirone, Vincenzo, Barletta, Francesco, Martini, Alberto, Bravi, Carlo Andrea, Cucchiara, Vito   +13 more
core   +1 more source